Rythmol and Atrial fibrillation/flutter - a phase IV clinical study of FDA data

Summary:

Atrial fibrillation/flutter is reported as a side effect among people who take Rythmol (propafenone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have High blood pressure.

The phase IV clinical study analyzes which people have Atrial fibrillation/flutter when taking Rythmol. It is created by eHealthMe based on reports of 3,422 people who have side effects when taking Rythmol from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 2,364 drugs and 3,841 conditions by eHealthMe. Check the latest studies of Atrial fibrillation/flutter.

On May, 08, 2026

3,422 people reported to have side effects when taking Rythmol.
Among them, 419 people (12.24%) have Atrial fibrillation/flutter.

Could Rythmol cause Atrial fibrillation/flutter?

Among these 419 people:

How long have people been on Rythmol when they have Atrial fibrillation/flutter? *

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What is the gender of people who have Atrial fibrillation/flutter when taking Rythmol? *

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What is the age of people who have Atrial fibrillation/flutter when taking Rythmol? *

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* Approximation only. Some reports may have incomplete information.

Do you take Rythmol and have Atrial fibrillation/flutter?

- Check whether Atrial fibrillation/flutter is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rythmol:

Rythmol (3,638 reports)

Atrial fibrillation/flutter treatments and more:

Atrial fibrillation/flutter (349,226 reports)

How severe was Atrial fibrillation/flutter and when was it recovered:

Atrial fibrillation/flutter in Rythmol

Expand to all the drugs that have ingredients of propafenone hydrochloride:

Atrial fibrillation/flutter and drugs with ingredients of propafenone hydrochloride (1,089 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rythmol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (2,364 drugs)

Browse all the conditions that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (3,841 conditions)

Related publications that referenced our studies

Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on propafenone hydrochloride (the active ingredients of Rythmol) and Rythmol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.