Rythmol and Indigestion - a phase IV clinical study of FDA data

Summary:

Indigestion is reported as a side effect among people who take Rythmol (propafenone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Pradaxa, and have High blood pressure.

The phase IV clinical study analyzes which people have Indigestion when taking Rythmol. It is created by eHealthMe based on reports of 3,422 people who have side effects when taking Rythmol from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Indigestion?

Indigestion is found to be associated with 2,413 drugs and 3,414 conditions by eHealthMe. Check the latest studies of Indigestion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 05, 2026

3,422 people reported to have side effects when taking Rythmol.
Among them, 40 people (1.17%) have Indigestion.

Among these 40 people:

How long have people been on Rythmol when they have Indigestion? *

What is the gender of people who have Indigestion when taking Rythmol? *

female: 74.36 %
male: 25.64 %

What is the age of people who have Indigestion when taking Rythmol? *

What are other drugs people take besides Rythmol? *

What are other side effects people have besides Indigestion? *

Fatigue (feeling of tiredness): 13 people, 32.50%
Nausea (feeling of having an urge to vomit): 13 people, 32.50%
Back Pain: 8 people, 20.00%
Diarrhea: 7 people, 17.50%
Abdominal Pain: 5 people, 12.50%
Dizziness: 5 people, 12.50%
Abdominal Pain Upper: 5 people, 12.50%
Feeling Abnormal: 5 people, 12.50%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 5 people, 12.50%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 12.50%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 25.00%
High Blood Cholesterol: 5 people, 12.50%
Insomnia (sleeplessness): 4 people, 10.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 7.50%
Sleep Disorder: 3 people, 7.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.50%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 7.50%
Pain: 2 people, 5.00%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Rythmol and have Indigestion?

- Check whether Indigestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rythmol:

Rythmol (3,638 reports)

Indigestion treatments and more:

Indigestion (445,030 reports)

Browse all side effects of Rythmol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Indigestion:

Indigestion (2,413 drugs)

Browse all the conditions that are associated with Indigestion:

Indigestion (3,414 conditions)

Related publications that referenced our studies

Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on propafenone hydrochloride (the active ingredients of Rythmol) and Rythmol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.