Saizen and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Saizen (somatropin recombinant), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Armour Thyroid, and have Growth hormone deficiency.

The phase IV clinical study analyzes which people have Weight increased when taking Saizen. It is created by eHealthMe based on reports of 3,115 people who have side effects when taking Saizen from the FDA, and is updated regularly.

What is Saizen?

Saizen has active ingredients of somatropin recombinant. eHealthMe is studying from 3,122 Saizen users. Check the latest studies of Saizen.

What is Weight increased?

Weight increased is found to be associated with 2,907 drugs and 3,891 conditions by eHealthMe. Check the latest studies of Weight increased.

On Oct, 31, 2025

3,115 people reported to have side effects when taking Saizen.
Among them, 22 people (0.71%) have Weight increased.

Among these 22 people:

How long have people been on Saizen when they have Weight increased? *

What is the gender of people who have Weight increased when taking Saizen? *

female: 61.9 %
male: 38.1 %

What is the age of people who have Weight increased when taking Saizen? *

What are other drugs people take besides Saizen? *

What are other side effects people have besides Weight increased? *

Fatigue (feeling of tiredness): 8 people, 36.36%
High Blood Pressure: 6 people, 27.27%
Headache (pain in head): 5 people, 22.73%
Bedridden: 5 people, 22.73%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 22.73%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 5 people, 22.73%
Insomnia (sleeplessness): 5 people, 22.73%
Hot Flush (sudden feelings of heat): 5 people, 22.73%
Drowsiness: 5 people, 22.73%
Overdose: 5 people, 22.73%

What are the existing conditions these people have? *

Growth Hormone Deficiency: 14 people, 63.64%
Pseudohypoparathyroidism (a condition associated primarily with resistance to the parathyroid hormone): 4 people, 18.18%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 9.09%
Primary Hypothyroidism (failure of the thyroid gland to produce or release thyroid hormones into the bloodstream): 1 person, 4.55%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.55%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.55%
Gonadotrophin Deficiency (lack of sex hormone): 1 person, 4.55%
Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 1 person, 4.55%
Cystitis Interstitial (unknown cause characterized by bladder pain): 1 person, 4.55%
Body Height Below Normal: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Saizen and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saizen:

Saizen (3,122 reports)

Weight increased treatments and more:

Weight increased (279,361 reports)

Browse all side effects of Saizen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,907 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,891 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on somatropin recombinant (the active ingredients of Saizen) and Saizen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.