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Salagen and Psoriasis - a phase IV clinical study of FDA data

Summary:

Psoriasis is reported as a side effect among people who take Salagen (pilocarpine hydrochloride), especially for people who are female, 60+ old, also take Cymbalta, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Psoriasis when taking Salagen. It is created by eHealthMe based on reports of 1,907 people who have side effects when taking Salagen from the FDA, and is updated regularly.

What is Salagen?

Salagen has active ingredients of pilocarpine hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,966 Salagen users. Check the latest studies of Salagen.

What is Psoriasis?

Psoriasis (immune-mediated disease that affects the skin) is found to be associated with 1,477 drugs and 1,694 conditions by eHealthMe. Check the latest studies of Psoriasis.

On Jul, 16, 2026

1,907 people reported to have side effects when taking Salagen.
Among them, 21 people (1.1%) have Psoriasis.

Could Salagen cause Psoriasis?

Among these 21 people:

What is the gender of people who have Psoriasis when taking Salagen? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Psoriasis when taking Salagen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 30 %
  • 60+: 50 %

What are other drugs people take besides Salagen? *

  1. Cymbalta: 9 people, 42.86%
  2. Tresiba: 7 people, 33.33%
  3. Methotrexate: 7 people, 33.33%
  4. Escitalopram: 7 people, 33.33%
  5. Fiasp: 7 people, 33.33%
  6. Humira: 6 people, 28.57%
  7. Cosentyx: 5 people, 23.81%
  8. Enbrel: 4 people, 19.05%
  9. Otezla: 4 people, 19.05%
  10. Inflectra: 4 people, 19.05%

What are other side effects people have besides Psoriasis? *

  1. Dry Eyes (lack of adequate tears): 7 people, 33.33%
  2. Joint Pain: 6 people, 28.57%
  3. Fatigue (feeling of tiredness): 6 people, 28.57%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 23.81%
  5. Anaemia (lack of blood): 5 people, 23.81%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 23.81%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 23.81%
  8. Depression: 4 people, 19.05%
  9. Head Injury: 4 people, 19.05%
  10. Malaise (a feeling of general discomfort or uneasiness): 3 people, 14.29%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 42.86%
  2. Insomnia (sleeplessness): 2 people, 9.52%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.52%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.52%
  5. Seasonal Allergy (allergic condition due to certain season): 1 person, 4.76%
  6. Pain: 1 person, 4.76%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 4.76%
  8. Neuralgia (pain in one or more nerves): 1 person, 4.76%
  9. Nausea (feeling of having an urge to vomit): 1 person, 4.76%
  10. Itching: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Salagen and have Psoriasis?

- Check whether Psoriasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Salagen:

Psoriasis treatments and more:

How severe was Psoriasis and when was it recovered:

Expand to all the drugs that have ingredients of pilocarpine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Salagen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psoriasis:

Browse all the conditions that are associated with Psoriasis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on pilocarpine hydrochloride (the active ingredients of Salagen) and Salagen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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