Savella and Abdominal pain aggravated - a phase IV clinical study of FDA data

Summary:

Abdominal pain aggravated is reported as a side effect among people who take Savella (milnacipran hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lyrica, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Abdominal pain aggravated when taking Savella. It is created by eHealthMe based on reports of 6,561 people who have side effects when taking Savella from the FDA, and is updated regularly.

What is Savella?

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. eHealthMe is studying from 7,529 Savella users. Check the latest studies of Savella.

What is Abdominal pain aggravated?

Abdominal pain aggravated (abdominal pain irritable) is found to be associated with 3,389 drugs and 3,459 conditions by eHealthMe. Check the latest studies of Abdominal pain aggravated.

On Aug, 08, 2026

6,561 people reported to have side effects when taking Savella.
Among them, 85 people (1.3%) have Abdominal pain aggravated.

Could Savella cause Abdominal pain aggravated?

Among these 85 people:

How long have people been on Savella when they have Abdominal pain aggravated? *

What is the gender of people who have Abdominal pain aggravated when taking Savella? *

female: 95.06 %
male: 4.94 %

What is the age of people who have Abdominal pain aggravated when taking Savella? *

What are other drugs people take besides Savella? *

What are other side effects people have besides Abdominal pain aggravated? *

Nausea (feeling of having an urge to vomit): 34 people, 40.00%
Diarrhea: 23 people, 27.06%
Nausea And Vomiting: 19 people, 22.35%
Headache (pain in head): 19 people, 22.35%
Hyperhidrosis (abnormally increased sweating): 17 people, 20.00%
Stress And Anxiety: 12 people, 14.12%
Constipation: 11 people, 12.94%
Weakness: 11 people, 12.94%
Dizziness: 11 people, 12.94%
Tremor (trembling or shaking movements in one or more parts of your body): 11 people, 12.94%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 14.12%
High Blood Pressure: 8 people, 9.41%
Stress And Anxiety: 7 people, 8.24%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.06%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 7.06%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 5.88%
Sleep Disorder: 5 people, 5.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 5.88%
Nausea (feeling of having an urge to vomit): 4 people, 4.71%
Insomnia (sleeplessness): 4 people, 4.71%

* Approximation only. Some reports may have incomplete information.

Do you take Savella and have Abdominal pain aggravated?

- Check whether Abdominal pain aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Savella:

Savella (7,529 reports)

Browse all side effects of Savella:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abdominal pain aggravated:

Abdominal pain aggravated (3,389 drugs)

Browse all the conditions that are associated with Abdominal pain aggravated:

Abdominal pain aggravated (3,459 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on milnacipran hydrochloride (the active ingredients of Savella) and Savella (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.