Saxenda and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Saxenda (liraglutide recombinant), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Benadryl, and have Depression.

The phase IV clinical study analyzes which people have Irritability when taking Saxenda. It is created by eHealthMe based on reports of 6,333 people who have side effects when taking Saxenda from the FDA, and is updated regularly.

What is Saxenda?

Saxenda has active ingredients of liraglutide recombinant. It is often used in weight loss. eHealthMe is studying from 6,735 Saxenda users. Check the latest studies of Saxenda.

What is Irritability?

Irritability is found to be associated with 1,700 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 12, 2026

6,333 people reported to have side effects when taking Saxenda.
Among them, 13 people (0.21%) have Irritability.

Among these 13 people:

How long have people been on Saxenda when they have Irritability? *

What is the gender of people who have Irritability when taking Saxenda? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Irritability when taking Saxenda? *

What are other drugs people take besides Saxenda? *

What are other side effects people have besides Irritability? *

Headache (pain in head): 8 people, 61.54%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 53.85%
Nausea (feeling of having an urge to vomit): 6 people, 46.15%
Itching: 5 people, 38.46%
Acne (skin problems that cause pimples): 5 people, 38.46%
Stress And Anxiety: 5 people, 38.46%
Memory Loss: 5 people, 38.46%
High Blood Pressure: 5 people, 38.46%
Fatigue (feeling of tiredness): 5 people, 38.46%
Pain: 4 people, 30.77%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 30.77%
Pain: 4 people, 30.77%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 30.77%
Depression: 4 people, 30.77%
Weight Decreased: 1 person, 7.69%
Sleep Disorder: 1 person, 7.69%
Insulin Resistance: 1 person, 7.69%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 7.69%
Dyslipidaemia (abnormal amount of lipids): 1 person, 7.69%
Cushing's Syndrome (obesity, a rounded face, increased fat): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Saxenda and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saxenda:

Saxenda (6,735 reports)

Irritability treatments and more:

Irritability (71,614 reports)

Browse all side effects of Saxenda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,700 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on liraglutide recombinant (the active ingredients of Saxenda) and Saxenda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.