Septra and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Septra (sulfamethoxazole; trimethoprim), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Aredia, and have Hiv infection.

The phase IV clinical study analyzes which people have Irritability when taking Septra. It is created by eHealthMe based on reports of 9,928 people who have side effects when taking Septra from the FDA, and is updated regularly.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

What is Irritability?

Irritability is found to be associated with 1,700 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 20, 2026

9,928 people reported to have side effects when taking Septra.
Among them, 40 people (0.4%) have Irritability.

Among these 40 people:

How long have people been on Septra when they have Irritability? *

What is the gender of people who have Irritability when taking Septra? *

female: 72.5 %
male: 27.5 %

What is the age of people who have Irritability when taking Septra? *

What are other drugs people take besides Septra? *

What are other side effects people have besides Irritability? *

Fatigue (feeling of tiredness): 27 people, 67.50%
Back Pain: 27 people, 67.50%
Pain: 25 people, 62.50%
Stress And Anxiety: 25 people, 62.50%
Joint Pain: 24 people, 60.00%
High Blood Pressure: 23 people, 57.50%
Dyspnea (difficult or laboured breathing): 23 people, 57.50%
Fever: 23 people, 57.50%
Chest Pain: 22 people, 55.00%
Nausea (feeling of having an urge to vomit): 22 people, 55.00%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 7.50%
Pain: 3 people, 7.50%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.50%
Hiv Infection: 3 people, 7.50%
Fatigue (feeling of tiredness): 2 people, 5.00%
Pneumonia: 2 people, 5.00%
T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 2 people, 5.00%
Dysmenorrhea (painful menstruation): 2 people, 5.00%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 2.50%
Anaemia (lack of blood): 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Septra and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Septra:

Septra (10,280 reports)

Irritability treatments and more:

Irritability (71,614 reports)

How severe was Irritability and when was it recovered:

Irritability in Septra

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Irritability and drugs with ingredients of sulfamethoxazole; trimethoprim (367 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Septra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,700 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Septra) and Septra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.