Seroquel and Angular cheilitis - a phase IV clinical study of FDA data

Summary:

Angular cheilitis is reported only by a few people who take Seroquel.

The study analyzes which people take Seroquel and have Angular cheilitis. It is created by eHealthMe based on reports of 113,615 people who have side effects while taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Angular cheilitis?

Angular cheilitis (inflammation of one, or more commonly both, of the corners of the mouth) is found to be associated with 74 drugs and 243 conditions by eHealthMe. Check the latest studies of Angular cheilitis.



On Jan, 21, 2026

113,615 people reported to have side effects when taking Seroquel.
Among them, 5 people (0.0%) have Angular cheilitis.

Could Seroquel cause Angular cheilitis?

Among these 5 people:

How long have people been on Seroquel when they have Angular cheilitis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Angular cheilitis when taking Seroquel? *

  • female: 20 %
  • male: 80 %

What is the age of people who have Angular cheilitis when taking Seroquel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 20 %
  • 30-39: 0.0 %
  • 40-49: 60 %
  • 50-59: 20 %
  • 60+: 0.0 %

What are other drugs people take besides Seroquel? *

  1. Vyvanse: 1 person, 20.00%
  2. Lexapro: 1 person, 20.00%
  3. Cymbalta: 1 person, 20.00%

What are other side effects people have besides Angular cheilitis? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 80.00%
  2. Headache (pain in head): 4 people, 80.00%
  3. Weight Increased: 3 people, 60.00%
  4. Hyperhidrosis (abnormally increased sweating): 3 people, 60.00%
  5. Gastritis (inflammation of stomach): 3 people, 60.00%
  6. Genital Burning Sensation: 3 people, 60.00%
  7. Haematocrit Increased: 3 people, 60.00%
  8. Haemoglobin Increased: 3 people, 60.00%
  9. High Blood Cholesterol: 3 people, 60.00%
  10. Indigestion: 3 people, 60.00%

What are the existing conditions these people have? *

  1. Constipation: 1 person, 20.00%
  2. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Angular cheilitis?

- Check whether Angular cheilitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Angular cheilitis treatments and more:

How severe was Angular cheilitis and when was it recovered:

Expand to all the drugs that have ingredients of quetiapine fumarate:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angular cheilitis:

Browse all the conditions that are associated with Angular cheilitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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