Seroquel and Bipolar ii disorder - a phase IV clinical study of FDA data

Summary:

Bipolar ii disorder is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Xanax, and have Narcolepsy.

The phase IV clinical study analyzes which people have Bipolar ii disorder when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Bipolar ii disorder?

Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression) is found to be associated with 92 drugs and 360 conditions by eHealthMe. Check the latest studies of Bipolar ii disorder.

On Jul, 17, 2026

113,615 people reported to have side effects when taking Seroquel.
Among them, 42 people (0.04%) have Bipolar ii disorder.

Could Seroquel cause Bipolar ii disorder?

Among these 42 people:

How long have people been on Seroquel when they have Bipolar ii disorder? *

What is the gender of people who have Bipolar ii disorder when taking Seroquel? *

female: 87.8 %
male: 12.2 %

What is the age of people who have Bipolar ii disorder when taking Seroquel? *

What are other drugs people take besides Seroquel? *

What are other side effects people have besides Bipolar ii disorder? *

Stress And Anxiety: 13 people, 30.95%
Borderline Personality Disorder: 11 people, 26.19%
Drug Ineffective: 9 people, 21.43%
Suicidal Ideation: 9 people, 21.43%
Constipation: 7 people, 16.67%
Alcoholism (problems with alcohol): 7 people, 16.67%
Back Pain: 6 people, 14.29%
Mitral Valve Incompetence (inefficient heart valve): 6 people, 14.29%
Fatigue (feeling of tiredness): 6 people, 14.29%
General Physical Health Deterioration (weak health status): 6 people, 14.29%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 19.05%
Birth Control: 6 people, 14.29%
Stress And Anxiety: 5 people, 11.90%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 11.90%
Sleep Disorder: 4 people, 9.52%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 7.14%
Affective Disorder (mental disorder): 3 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.76%
Pain: 2 people, 4.76%
Migraine (headache): 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Bipolar ii disorder?

- Check whether Bipolar ii disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Seroquel (120,285 reports)

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bipolar ii disorder:

Bipolar ii disorder (92 drugs)

Browse all the conditions that are associated with Bipolar ii disorder:

Bipolar ii disorder (360 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.