Seroquel and Hypospadias - a phase IV clinical study of FDA data

Summary:

Hypospadias is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are 0-1 old, also take Brintellix, and have Generalized anxiety disorder.

The phase IV clinical study analyzes which people have Hypospadias when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Hypospadias?

Hypospadias (an abnormal condition in males in which the urethra opens on the under surface of the penis) is found to be associated with 138 drugs and 59 conditions by eHealthMe. Check the latest studies of Hypospadias.

On Jul, 05, 2026

113,615 people reported to have side effects when taking Seroquel.
Among them, 17 people (0.01%) have Hypospadias.

Among these 17 people:

What is the age of people who have Hypospadias when taking Seroquel? *

What are other drugs people take besides Seroquel? *

What are other side effects people have besides Hypospadias? *

Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 5 people, 29.41%
Drug Exposure During Pregnancy: 3 people, 17.65%
Respiratory Distress Syndrome (Rds) In Infants (respiratory disease of newborn babies, especially premature babies, characterized by distressful breathing, cyanosis, and the formation of a glassy membrane over the alveoli of the lungs): 3 people, 17.65%
Premature Baby: 2 people, 11.76%
Feeding Disorder Neonatal (when newborn refuse to drink milk): 2 people, 11.76%
Fever: 2 people, 11.76%
Cough: 2 people, 11.76%
Joint Ankylosis (a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint): 2 people, 11.76%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 11.76%
Trismus (reduced opening of the jaws): 2 people, 11.76%

What are the existing conditions these people have? *

Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 11.76%
Supraventricular Extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 1 person, 5.88%
Stress And Anxiety: 1 person, 5.88%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 5.88%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 5.88%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 5.88%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 5.88%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Hypospadias?

- Check whether Hypospadias is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Seroquel (120,285 reports)

Hypospadias treatments and more:

Hypospadias (2,613 reports)

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypospadias:

Hypospadias (138 drugs)

Browse all the conditions that are associated with Hypospadias:

Hypospadias (59 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.