Seroquel and Onychoclasis - a phase IV clinical study of FDA data

Summary:

Onychoclasis is reported as a side effect among people who take Seroquel (quetiapine fumarate), especially for people who are female, 60+ old, also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Onychoclasis when taking Seroquel. It is created by eHealthMe based on reports of 113,615 people who have side effects when taking Seroquel from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Onychoclasis?

Onychoclasis (breaking of the nails) is found to be associated with 616 drugs and 607 conditions by eHealthMe. Check the latest studies of Onychoclasis.

On Jul, 04, 2026

113,615 people reported to have side effects when taking Seroquel.
Among them, 24 people (0.02%) have Onychoclasis.

Among these 24 people:

What is the gender of people who have Onychoclasis when taking Seroquel? *

female: 100 %
male: 0.0 %

What is the age of people who have Onychoclasis when taking Seroquel? *

What are other drugs people take besides Seroquel? *

What are other side effects people have besides Onychoclasis? *

Nausea (feeling of having an urge to vomit): 14 people, 58.33%
Nausea And Vomiting: 11 people, 45.83%
Fatigue (feeling of tiredness): 10 people, 41.67%
Hair Loss: 10 people, 41.67%
Weight Decreased: 8 people, 33.33%
Joint Pain: 8 people, 33.33%
Chest Pain: 8 people, 33.33%
Neutrophil Count Abnormal (abnormal number of neutrophil a type of blood cell): 7 people, 29.17%
Dizziness: 7 people, 29.17%
Migraine (headache): 7 people, 29.17%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 45.83%
Pain: 11 people, 45.83%
Sleep Disorder: 7 people, 29.17%
Breast Cancer: 7 people, 29.17%
Sedation: 7 people, 29.17%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 29.17%
Gastric Disorder (disease of stomach): 7 people, 29.17%
Stress And Anxiety: 6 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 20.83%
Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 20.83%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Onychoclasis?

- Check whether Onychoclasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Seroquel:

Seroquel (120,285 reports)

Onychoclasis treatments and more:

Onychoclasis (7,925 reports)

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Onychoclasis:

Onychoclasis (616 drugs)

Browse all the conditions that are associated with Onychoclasis:

Onychoclasis (607 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.