Sertraline and Arterial disorder - a phase IV clinical study of FDA data

Summary:

Arterial disorder is reported as a side effect among people who take Sertraline (sertraline hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Acetaminophen, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Arterial disorder when taking Sertraline. It is created by eHealthMe based on reports of 146,463 people who have side effects when taking Sertraline from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,308 Sertraline users. Check the latest studies of Sertraline.

What is Arterial disorder?

Arterial disorder is found to be associated with 327 drugs and 475 conditions by eHealthMe. Check the latest studies of Arterial disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

146,463 people reported to have side effects when taking Sertraline.
Among them, 25 people (0.02%) have Arterial disorder.

Could Sertraline cause Arterial disorder?

Among these 25 people:

How long have people been on Sertraline when they have Arterial disorder? *

What is the gender of people who have Arterial disorder when taking Sertraline? *

female: 27.27 %
male: 72.73 %

What is the age of people who have Arterial disorder when taking Sertraline? *

What are other drugs people take besides Sertraline? *

What are other side effects people have besides Arterial disorder? *

Fatigue (feeling of tiredness): 18 people, 72.00%
Chest Pain: 12 people, 48.00%
Dyspnea (difficult or laboured breathing): 10 people, 40.00%
Dizziness: 10 people, 40.00%
Pain In Extremity: 9 people, 36.00%
Joint Pain: 9 people, 36.00%
Headache (pain in head): 9 people, 36.00%
Nausea (feeling of having an urge to vomit): 9 people, 36.00%
Cataract (clouding of the lens inside the eye): 8 people, 32.00%
Appetite Disorder (abnormal eating habits): 8 people, 32.00%

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 32.00%
High Blood Cholesterol: 8 people, 32.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 32.00%
Weight Decreased: 7 people, 28.00%
Weight Loss: 6 people, 24.00%
Renal Disorder (kidney disease): 6 people, 24.00%
Pain: 5 people, 20.00%
Immunodeficiency Common Variable: 4 people, 16.00%
Renal Impairment (severely reduced kidney function): 2 people, 8.00%
Primary Immunodeficiency Syndrome: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sertraline and have Arterial disorder?

- Check whether Arterial disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sertraline:

Sertraline (153,308 reports)

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arterial disorder:

Arterial disorder (327 drugs)

Browse all the conditions that are associated with Arterial disorder:

Arterial disorder (475 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Sertraline) and Sertraline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.