Serzone and Coronary artery occlusion - a phase IV clinical study of FDA data

Summary:

Coronary artery occlusion is reported as a side effect among people who take Serzone (nefazodone hydrochloride), especially for people who are male, 50-59 old, also take Vioxx, and have High blood pressure.

The phase IV clinical study analyzes which people have Coronary artery occlusion when taking Serzone. It is created by eHealthMe based on reports of 7,594 people who have side effects when taking Serzone from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Coronary artery occlusion?

Coronary artery occlusion (complete obstruction of blood flow in a coronary artery) is found to be associated with 950 drugs and 1,059 conditions by eHealthMe. Check the latest studies of Coronary artery occlusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

7,594 people reported to have side effects when taking Serzone.
Among them, 16 people (0.21%) have Coronary artery occlusion.

Could Serzone cause Coronary artery occlusion?

Among these 16 people:

What is the gender of people who have Coronary artery occlusion when taking Serzone? *

female: 31.25 %
male: 68.75 %

What is the age of people who have Coronary artery occlusion when taking Serzone? *

What are other drugs people take besides Serzone? *

What are other side effects people have besides Coronary artery occlusion? *

Chest Pain: 14 people, 87.50%
High Blood Pressure: 12 people, 75.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 12 people, 75.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 11 people, 68.75%
Back Pain: 10 people, 62.50%
Heart Attack: 8 people, 50.00%
Cardiac Arrest: 8 people, 50.00%
Intervertebral Disc Protrusion (spinal disc protrusion): 8 people, 50.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 50.00%
Dyspnea (difficult or laboured breathing): 7 people, 43.75%

What are the existing conditions these people have? *

Pain In Extremity: 8 people, 50.00%
High Blood Pressure: 8 people, 50.00%
Joint Pain: 3 people, 18.75%
Post-Traumatic Stress Disorder: 1 person, 6.25%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Serzone and have Coronary artery occlusion?

- Check whether Coronary artery occlusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Serzone:

Serzone (7,695 reports)

Browse all side effects of Serzone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coronary artery occlusion:

Coronary artery occlusion (950 drugs)

Browse all the conditions that are associated with Coronary artery occlusion:

Coronary artery occlusion (1,059 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nefazodone hydrochloride (the active ingredients of Serzone) and Serzone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.