Sevoflurane and Mental status changes - a phase IV clinical study of FDA data

Summary:

Mental status changes is reported as a side effect among people who take Sevoflurane (sevoflurane), especially for people who are male, 20-29 old, have been taking the drug for < 1 month also take Ondansetron, and have Depression.

The phase IV clinical study analyzes which people have Mental status changes when taking Sevoflurane. It is created by eHealthMe based on reports of 9,502 people who have side effects when taking Sevoflurane from the FDA, and is updated regularly.

What is Sevoflurane?

Sevoflurane has active ingredients of sevoflurane. eHealthMe is studying from 9,513 Sevoflurane users. Check the latest studies of Sevoflurane.

What is Mental status changes?

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) is found to be associated with 1,498 drugs and 1,759 conditions by eHealthMe. Check the latest studies of Mental status changes.



On Jul, 11, 2026

9,502 people reported to have side effects when taking Sevoflurane.
Among them, 14 people (0.15%) have Mental status changes.

Could Sevoflurane cause Mental status changes?

Among these 14 people:

How long have people been on Sevoflurane when they have Mental status changes? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Mental status changes when taking Sevoflurane? *

  • female: 45.45 %
  • male: 54.55 %

What is the age of people who have Mental status changes when taking Sevoflurane? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 30 %
  • 20-29: 40 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 0.0 %
  • 60+: 20 %

What are other drugs people take besides Sevoflurane? *

  1. Ondansetron: 9 people, 64.29%
  2. Heparin: 4 people, 28.57%
  3. Propofol: 4 people, 28.57%
  4. Methotrexate: 2 people, 14.29%
  5. Percocet: 2 people, 14.29%
  6. Cefazolin: 2 people, 14.29%
  7. Fentanyl: 2 people, 14.29%
  8. Fluconazole: 2 people, 14.29%
  9. Oncaspar: 2 people, 14.29%
  10. Acetaminophen: 2 people, 14.29%

What are other side effects people have besides Mental status changes? *

  1. Agitation (state of anxiety or nervous excitement): 7 people, 50.00%
  2. High Blood Pressure: 6 people, 42.86%
  3. Muscle Rigidity (muscle stiffness): 5 people, 35.71%
  4. Arrhythmias (irregular heartbeat): 5 people, 35.71%
  5. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 4 people, 28.57%
  6. Tachypnea: 4 people, 28.57%
  7. Crying: 3 people, 21.43%
  8. Aggression: 2 people, 14.29%
  9. Unresponsive To Stimuli: 2 people, 14.29%
  10. Screaming (a long loud piercing cry): 2 people, 14.29%

What are the existing conditions these people have? *

  1. Systemic Candida (whole body fungal infection): 4 people, 28.57%
  2. Pain: 4 people, 28.57%
  3. Muscle Aches (muscle pain): 4 people, 28.57%
  4. Depression: 4 people, 28.57%
  5. Nightmares (unpleasant dreams): 3 people, 21.43%
  6. Pyogenic Liver Abscess (liver abscess caused by bacteria): 2 people, 14.29%
  7. Nausea And Vomiting: 2 people, 14.29%
  8. Anaesthesia: 2 people, 14.29%
  9. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 7.14%
  10. Post-Traumatic Stress Disorder: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Sevoflurane and have Mental status changes?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sevoflurane:

Mental status changes treatments and more:

How severe was Mental status changes and when was it recovered:

Expand to all the drugs that have ingredients of sevoflurane:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sevoflurane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental status changes:

Browse all the conditions that are associated with Mental status changes:


How the study uses the data?

The study uses data from the FDA. It is based on sevoflurane (the active ingredients of Sevoflurane) and Sevoflurane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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