Signifor and Heart palpitations - a phase IV clinical study of FDA data

Summary:

Heart palpitations is reported as a side effect among people who take Signifor (pasireotide diaspartate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Metformin, and have Pituitary-dependent cushing's syndrome.

The phase IV clinical study analyzes which people have Heart palpitations when taking Signifor. It is created by eHealthMe based on reports of 886 people who have side effects when taking Signifor from the FDA, and is updated regularly.

What is Signifor?

Signifor has active ingredients of pasireotide diaspartate. eHealthMe is studying from 887 Signifor users. Check the latest studies of Signifor.

What is Heart palpitations?

Heart palpitations (feelings or sensations that your heart is pounding or racing) is found to be associated with 2,443 drugs and 3,638 conditions by eHealthMe. Check the latest studies of Heart palpitations.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

886 people reported to have side effects when taking Signifor.
Among them, 17 people (1.92%) have Heart palpitations.

Could Signifor cause Heart palpitations?

Among these 17 people:

How long have people been on Signifor when they have Heart palpitations? *

What is the gender of people who have Heart palpitations when taking Signifor? *

female: 100 %
male: 0.0 %

What is the age of people who have Heart palpitations when taking Signifor? *

What are other drugs people take besides Signifor? *

What are other side effects people have besides Heart palpitations? *

Dizziness: 13 people, 76.47%
Fatigue (feeling of tiredness): 12 people, 70.59%
Insomnia (sleeplessness): 10 people, 58.82%
Nausea (feeling of having an urge to vomit): 10 people, 58.82%
Hyperhidrosis (abnormally increased sweating): 7 people, 41.18%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 41.18%
High Blood Pressure: 6 people, 35.29%
Weight Increased: 6 people, 35.29%
Heart Rate Increased: 6 people, 35.29%
Injection Site Erythema (redness at injection site): 6 people, 35.29%

What are the existing conditions these people have? *

Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 10 people, 58.82%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 41.18%
Cushing's Syndrome (obesity, a rounded face, increased fat): 6 people, 35.29%
Depression: 2 people, 11.76%
Pituitary Tumor Benign: 1 person, 5.88%
Nelson's Syndrome (rapid enlargement of a pituitary tumour that occurs after the removal of both adrenal glands): 1 person, 5.88%
Cellulitis (infection under the skin): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Signifor and have Heart palpitations?

- Check whether Heart palpitations is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Signifor:

Signifor (887 reports)

Browse all side effects of Signifor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart palpitations:

Heart palpitations (2,443 drugs)

Browse all the conditions that are associated with Heart palpitations:

Heart palpitations (3,638 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pasireotide diaspartate (the active ingredients of Signifor) and Signifor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.