Simethicone and Nephropathy - a phase IV clinical study of FDA data

Summary:

Nephropathy is reported as a side effect among people who take Simethicone (simethicone), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Prilosec, and have Pain.

The phase IV clinical study analyzes which people have Nephropathy when taking Simethicone. It is created by eHealthMe based on reports of 6,434 people who have side effects when taking Simethicone from the FDA, and is updated regularly.

What is Simethicone?

Simethicone has active ingredients of simethicone. It is often used in gas. eHealthMe is studying from 6,763 Simethicone users. Check the latest studies of Simethicone.

What is Nephropathy?

Nephropathy (damage to or disease of a kidney) is found to be associated with 896 drugs and 736 conditions by eHealthMe. Check the latest studies of Nephropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

6,434 people reported to have side effects when taking Simethicone.
Among them, 14 people (0.22%) have Nephropathy.

Among these 14 people:

How long have people been on Simethicone when they have Nephropathy? *

What is the gender of people who have Nephropathy when taking Simethicone? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Nephropathy when taking Simethicone? *

What are other drugs people take besides Simethicone? *

What are other side effects people have besides Nephropathy? *

Acute Kidney Failure: 13 people, 92.86%
Chronic Kidney Disease: 11 people, 78.57%
Interstitial Nephritis (inflammation of the kidney): 9 people, 64.29%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 28.57%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 28.57%
Multiple Myeloma (cancer of the plasma cells): 4 people, 28.57%
Emotional Distress: 3 people, 21.43%
Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 14.29%
Tooth Loss: 2 people, 14.29%
Pain: 2 people, 14.29%

What are the existing conditions these people have? *

Pain: 9 people, 64.29%
Hypersensitivity: 7 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 50.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 42.86%
Stable Angina (a constant chest pain): 5 people, 35.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 35.71%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 35.71%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Nasal Dryness (dry nose): 5 people, 35.71%

* Approximation only. Some reports may have incomplete information.

Do you take Simethicone and have Nephropathy?

- Check whether Nephropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simethicone:

Simethicone (6,763 reports)

Nephropathy treatments and more:

Nephropathy (16,529 reports)

Browse all side effects of Simethicone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephropathy:

Nephropathy (896 drugs)

Browse all the conditions that are associated with Nephropathy:

Nephropathy (736 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simethicone (the active ingredients of Simethicone) and Simethicone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.