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Simponi and Atrioventricular block complete - a phase IV clinical study of FDA data

Summary:

Atrioventricular block complete is reported as a side effect among people who take Simponi (golimumab), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Arava, and have Sepsis.

The phase IV clinical study analyzes which people have Atrioventricular block complete when taking Simponi. It is created by eHealthMe based on reports of 86,103 people who have side effects when taking Simponi from the FDA, and is updated regularly.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

What is Atrioventricular block complete?

Atrioventricular block complete (heart block complete) is found to be associated with 672 drugs and 949 conditions by eHealthMe. Check the latest studies of Atrioventricular block complete.

On Jul, 16, 2026

86,103 people reported to have side effects when taking Simponi.
Among them, 13 people (0.02%) have Atrioventricular block complete.

Could Simponi cause Atrioventricular block complete?

Among these 13 people:

How long have people been on Simponi when they have Atrioventricular block complete? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Atrioventricular block complete when taking Simponi? *

  • female: 7.69 %
  • male: 92.31 %

What is the age of people who have Atrioventricular block complete when taking Simponi? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Simponi? *

  1. Xeljanz: 6 people, 46.15%
  2. Stelara: 6 people, 46.15%
  3. Humira: 6 people, 46.15%
  4. Arava: 6 people, 46.15%
  5. Pantoprazole: 4 people, 30.77%
  6. Methotrexate: 2 people, 15.38%
  7. Sulfasalazine: 1 person, 7.69%
  8. Remicade: 1 person, 7.69%
  9. Prednisone: 1 person, 7.69%
  10. Leucovorin Calcium: 1 person, 7.69%

What are other side effects people have besides Atrioventricular block complete? *

  1. Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 46.15%
  2. Nausea (feeling of having an urge to vomit): 6 people, 46.15%
  3. Joint Swelling: 6 people, 46.15%
  4. Joint Pain: 6 people, 46.15%
  5. Diarrhea: 6 people, 46.15%
  6. Drug Ineffective: 6 people, 46.15%
  7. Bradycardia (abnormally slow heart action): 5 people, 38.46%
  8. Whipple's Disease (infection with a bacteria called tropheryma whippelii): 1 person, 7.69%
  9. Heart Attack: 1 person, 7.69%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 46.15%
  2. Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 46.15%
  3. Nausea (feeling of having an urge to vomit): 5 people, 38.46%
  4. Aortic Valve Incompetence: 4 people, 30.77%
  5. Diabetes: 1 person, 7.69%
  6. Acne (skin problems that cause pimples): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Simponi and have Atrioventricular block complete?

- Check whether Atrioventricular block complete is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simponi:

Atrioventricular block complete treatments and more:

How severe was Atrioventricular block complete and when was it recovered:

Expand to all the drugs that have ingredients of golimumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simponi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrioventricular block complete:

Browse all the conditions that are associated with Atrioventricular block complete:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on golimumab (the active ingredients of Simponi) and Simponi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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