Simponi and Intervertebral disc compression - a phase IV clinical study of FDA data

Summary:

Intervertebral disc compression is reported as a side effect among people who take Simponi (golimumab), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Arava,.

The phase IV clinical study analyzes which people have Intervertebral disc compression when taking Simponi. It is created by eHealthMe based on reports of 86,103 people who have side effects when taking Simponi from the FDA, and is updated regularly.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

What is Intervertebral disc compression?

Intervertebral disc compression (spinal disc compression) is found to be associated with 285 drugs and 286 conditions by eHealthMe. Check the latest studies of Intervertebral disc compression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

86,103 people reported to have side effects when taking Simponi.
Among them, 66 people (0.08%) have Intervertebral disc compression.

Could Simponi cause Intervertebral disc compression?

Among these 66 people:

How long have people been on Simponi when they have Intervertebral disc compression? *

What is the gender of people who have Intervertebral disc compression when taking Simponi? *

female: 100 %
male: 0.0 %

What is the age of people who have Intervertebral disc compression when taking Simponi? *

What are other drugs people take besides Simponi? *

What are other side effects people have besides Intervertebral disc compression? *

Joint Swelling: 57 people, 86.36%
Peripheral Swelling: 56 people, 84.85%
Joint Pain: 56 people, 84.85%
Back Injury: 55 people, 83.33%
Drug Ineffective: 55 people, 83.33%
Pain: 55 people, 83.33%
Joint Stiffness: 55 people, 83.33%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 55 people, 83.33%
Back Pain: 55 people, 83.33%
Intervertebral Disc Space Narrowing (spinal disc space narrowing): 54 people, 81.82%

* Approximation only. Some reports may have incomplete information.

Do you take Simponi and have Intervertebral disc compression?

- Check whether Intervertebral disc compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Simponi:

Simponi (86,328 reports)

Browse all side effects of Simponi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc compression:

Intervertebral disc compression (285 drugs)

Browse all the conditions that are associated with Intervertebral disc compression:

Intervertebral disc compression (286 conditions)

Related publications that referenced our studies

Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on golimumab (the active ingredients of Simponi) and Simponi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.