Sinemet and Accident - a phase IV clinical study of FDA data

Summary:

Accident is reported as a side effect among people who take Sinemet (carbidopa; levodopa), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Neupro, and have Delusion.

The phase IV clinical study analyzes which people have Accident when taking Sinemet. It is created by eHealthMe based on reports of 28,351 people who have side effects when taking Sinemet from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Accident?

Accident is found to be associated with 871 drugs and 865 conditions by eHealthMe. Check the latest studies of Accident.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

28,351 people reported to have side effects when taking Sinemet.
Among them, 42 people (0.15%) have Accident.

Among these 42 people:

How long have people been on Sinemet when they have Accident? *

What is the gender of people who have Accident when taking Sinemet? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Accident when taking Sinemet? *

What are other drugs people take besides Sinemet? *

What are other side effects people have besides Accident? *

Weight Decreased: 14 people, 33.33%
Confusional State: 13 people, 30.95%
Dyspnea (difficult or laboured breathing): 10 people, 23.81%
Campylobacter Infection (infection by the campylobacter bacterium): 9 people, 21.43%
Skin Discoloration - Bluish (bluish colour of skin): 9 people, 21.43%
Muscle Function Loss: 9 people, 21.43%
Mental Impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 9 people, 21.43%
Nausea And Vomiting: 9 people, 21.43%
Parkinsonian Crisis: 9 people, 21.43%
Delirium (wild excitement): 9 people, 21.43%

What are the existing conditions these people have? *

Delusion (a false belief or opinion): 11 people, 26.19%
Hyperchlorhydria (gastric acid levels are higher in stomach): 9 people, 21.43%
Campylobacter Infection (infection by the campylobacter bacterium): 9 people, 21.43%
Agitation (state of anxiety or nervous excitement): 9 people, 21.43%
Sleep Disorder: 3 people, 7.14%
Excessive Granulation Tissue (excessive collagen-rich tissue which forms at the site of an injury): 3 people, 7.14%
Pain: 2 people, 4.76%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 4.76%
Wound Complication: 1 person, 2.38%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 2.38%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and have Accident?

- Check whether Accident is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinemet:

Sinemet (29,601 reports)

Accident treatments and more:

Accident (13,677 reports)

Browse all side effects of Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Accident:

Accident (871 drugs)

Browse all the conditions that are associated with Accident:

Accident (865 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa (the active ingredients of Sinemet) and Sinemet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.