Sinequan and Neuralgia - a phase IV clinical study of FDA data

Summary:

Neuralgia is reported as a side effect among people who take Sinequan (doxepin hydrochloride), especially for people who are female, 50-59 old, also take Neurontin, and have Breast cancer.

The phase IV clinical study analyzes which people have Neuralgia when taking Sinequan. It is created by eHealthMe based on reports of 1,788 people who have side effects when taking Sinequan from the FDA, and is updated regularly.

What is Sinequan?

Sinequan has active ingredients of doxepin hydrochloride. It is often used in depression. eHealthMe is studying from 1,879 Sinequan users. Check the latest studies of Sinequan.

What is Neuralgia?

Neuralgia (pain in one or more nerves) is found to be associated with 1,390 drugs and 1,786 conditions by eHealthMe. Check the latest studies of Neuralgia.

On Jul, 11, 2026

1,788 people reported to have side effects when taking Sinequan.
Among them, 15 people (0.84%) have Neuralgia.

Among these 15 people:

What is the gender of people who have Neuralgia when taking Sinequan? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Neuralgia when taking Sinequan? *

What are other drugs people take besides Sinequan? *

What are other side effects people have besides Neuralgia? *

Fall: 13 people, 86.67%
Pain: 13 people, 86.67%
Nausea And Vomiting: 13 people, 86.67%
Hypoaesthesia (reduced sense of touch or sensation): 12 people, 80.00%
Fever: 12 people, 80.00%
Flatulence (flatus expelled through the anus): 12 people, 80.00%
Foot Deformity (functional disability of foot): 12 people, 80.00%
Foot Fracture: 12 people, 80.00%
Gastrointestinal Inflammation (inflammation of stomach and intestine): 12 people, 80.00%
Genital Herpes (herpes infection of genital): 12 people, 80.00%

What are the existing conditions these people have? *

Breast Cancer: 8 people, 53.33%
Osteoporosis (bones weak and more likely to break): 4 people, 26.67%
Multiple Myeloma (cancer of the plasma cells): 4 people, 26.67%
Metastases To Bone (cancer spreads to bone): 4 people, 26.67%
Sleep Disorder: 1 person, 6.67%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.67%
Rashes (redness): 1 person, 6.67%
Nervousness: 1 person, 6.67%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 6.67%
Muscle Spasms (muscle contraction): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sinequan and have Neuralgia?

- Check whether Neuralgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sinequan:

Sinequan (1,879 reports)

Neuralgia treatments and more:

Neuralgia (81,600 reports)

Browse all side effects of Sinequan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neuralgia:

Neuralgia (1,390 drugs)

Browse all the conditions that are associated with Neuralgia:

Neuralgia (1,786 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxepin hydrochloride (the active ingredients of Sinequan) and Sinequan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.