Sirolimus and Hypokalemia - a phase IV clinical study of FDA data

Summary:

Hypokalemia is reported as a side effect among people who take Sirolimus (sirolimus), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Posaconazole, and have Cytomegalovirus viraemia.

The phase IV clinical study analyzes which people have Hypokalemia when taking Sirolimus. It is created by eHealthMe based on reports of 11,812 people who have side effects when taking Sirolimus from the FDA, and is updated regularly.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

What is Hypokalemia?

Hypokalemia (low potassium) is found to be associated with 2,091 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Hypokalemia.

On Jul, 20, 2026

11,812 people reported to have side effects when taking Sirolimus.
Among them, 86 people (0.73%) have Hypokalemia.

Among these 86 people:

How long have people been on Sirolimus when they have Hypokalemia? *

What is the gender of people who have Hypokalemia when taking Sirolimus? *

female: 68.83 %
male: 31.17 %

What is the age of people who have Hypokalemia when taking Sirolimus? *

What are other drugs people take besides Sirolimus? *

Levofloxacin: 14 people, 16.28%
Posaconazole: 14 people, 16.28%
Acyclovir: 13 people, 15.12%
Methylprednisolone: 12 people, 13.95%
Ganciclovir: 12 people, 13.95%
Amphotericin B: 11 people, 12.79%
Cyclosporine: 11 people, 12.79%
Mycophenolate Mofetil: 11 people, 12.79%
Voriconazole: 11 people, 12.79%
Meropenem: 11 people, 12.79%

What are other side effects people have besides Hypokalemia? *

Acute Kidney Failure: 26 people, 30.23%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 24 people, 27.91%
Diarrhea: 23 people, 26.74%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 20 people, 23.26%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 16 people, 18.60%
Diabetes Insipidus - Nephrogenic (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 16 people, 18.60%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 14 people, 16.28%
Drug Ineffective: 14 people, 16.28%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 13 people, 15.12%
Anaemia (lack of blood): 12 people, 13.95%

What are the existing conditions these people have? *

Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 20 people, 23.26%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 16 people, 18.60%
Bone Marrow Conditioning Regimen: 9 people, 10.47%
Immunodeficiency Disorders: 7 people, 8.14%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 6.98%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 3.49%
Gastritis (inflammation of stomach): 2 people, 2.33%
Tumor: 2 people, 2.33%
Thrombocytopenia (decrease of platelets in blood): 2 people, 2.33%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sirolimus and have Hypokalemia?

- Check whether Hypokalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sirolimus:

Sirolimus (11,823 reports)

Hypokalemia treatments and more:

Hypokalemia (72,277 reports)

Browse all side effects of Sirolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypokalemia:

Hypokalemia (2,091 drugs)

Browse all the conditions that are associated with Hypokalemia:

Hypokalemia (3,091 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sirolimus (the active ingredients of Sirolimus) and Sirolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.