Sitagliptin and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Sitagliptin (sitagliptin), especially for people who are female, 60+ old, also take Ramipril, and have Bronchospasm.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Sitagliptin. It is created by eHealthMe based on reports of 3,929 people who have side effects when taking Sitagliptin from the FDA, and is updated regularly.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,496 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

3,929 people reported to have side effects when taking Sitagliptin.
Among them, 13 people (0.33%) have Liver function test abnormal.

Could Sitagliptin cause Liver function test abnormal?

Among these 13 people:

What is the gender of people who have Liver function test abnormal when taking Sitagliptin? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Liver function test abnormal when taking Sitagliptin? *

What are other drugs people take besides Sitagliptin? *

What are other side effects people have besides Liver function test abnormal? *

Abdominal Pain: 11 people, 84.62%
Abdominal Pain Upper: 8 people, 61.54%
Faeces Pale: 8 people, 61.54%
Diarrhea: 4 people, 30.77%
Nausea And Vomiting: 3 people, 23.08%
Choledocholithiasis (stones in the common bile duct): 3 people, 23.08%
Diabetic Ulcer: 1 person, 7.69%
Anaemia (lack of blood): 1 person, 7.69%
Back Pain: 1 person, 7.69%
Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 1 person, 7.69%

What are the existing conditions these people have? *

Type 2 Diabetes: 1 person, 7.69%
Stable Angina (a constant chest pain): 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 7.69%
Pain In Extremity: 1 person, 7.69%
Pain: 1 person, 7.69%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 7.69%
Diabetes: 1 person, 7.69%
Cardiac Failure: 1 person, 7.69%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Sitagliptin and have Liver function test abnormal?

- Check whether Liver function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sitagliptin:

Sitagliptin (3,933 reports)

Browse all side effects of Sitagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,497 drugs)

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin (the active ingredients of Sitagliptin) and Sitagliptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.