Sodium chloride and Freezing phenomenon - a phase IV clinical study of FDA data

Summary:

Freezing phenomenon is reported as a side effect among people who take Sodium chloride (sodium chloride), especially for people who are male, 60+ old, also take Mirabegron, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Freezing phenomenon when taking Sodium chloride. It is created by eHealthMe based on reports of 39,502 people who have side effects when taking Sodium chloride from the FDA, and is updated regularly.

What is Sodium chloride?

Sodium chloride has active ingredients of sodium chloride. eHealthMe is studying from 39,559 Sodium chloride users. Check the latest studies of Sodium chloride.

What is Freezing phenomenon?

Freezing phenomenon is found to be associated with 208 drugs and 231 conditions by eHealthMe. Check the latest studies of Freezing phenomenon.



On Jul, 31, 2026

39,502 people reported to have side effects when taking Sodium chloride.
Among them, 23 people (0.06%) have Freezing phenomenon.

Could Sodium chloride cause Freezing phenomenon?

Among these 23 people:

What is the gender of people who have Freezing phenomenon when taking Sodium chloride? *

  • female: 45 %
  • male: 55 %

What is the age of people who have Freezing phenomenon when taking Sodium chloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Sodium chloride? *

  1. Senna: 12 people, 52.17%
  2. Mirabegron: 12 people, 52.17%
  3. Sinemet: 10 people, 43.48%
  4. Clonazepam: 9 people, 39.13%
  5. Omeprazole: 9 people, 39.13%
  6. Vitamin D3: 8 people, 34.78%
  7. Naproxen: 6 people, 26.09%
  8. Amlodipine: 6 people, 26.09%
  9. Cyanocobalamin: 6 people, 26.09%
  10. Ibuprofen: 6 people, 26.09%

What are other side effects people have besides Freezing phenomenon? *

  1. Mobility Decreased (ability to move is reduced): 20 people, 86.96%
  2. Muscle Rigidity (muscle stiffness): 19 people, 82.61%
  3. Stress And Anxiety: 19 people, 82.61%
  4. Fall: 19 people, 82.61%
  5. Urination - Excessive At Night: 17 people, 73.91%
  6. Weakness: 15 people, 65.22%
  7. Dyskinesia (abnormality or impairment of voluntary movement): 15 people, 65.22%
  8. Weight Decreased: 14 people, 60.87%
  9. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases): 14 people, 60.87%
  10. On And Off Phenomenon: 14 people, 60.87%

What are the existing conditions these people have? *

  1. Parkinson's Disease: 22 people, 95.65%
  2. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 9 people, 39.13%
  3. Abnormal Faeces (abnormal stool): 2 people, 8.70%
  4. Urination - Excessive At Night: 1 person, 4.35%
  5. Laxative Supportive Care: 1 person, 4.35%
  6. Constipation: 1 person, 4.35%
  7. Bowel Movement Irregularity: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Sodium chloride and have Freezing phenomenon?

- Check whether Freezing phenomenon is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sodium chloride:

Freezing phenomenon treatments and more:

How severe was Freezing phenomenon and when was it recovered:

Expand to all the drugs that have ingredients of sodium chloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sodium chloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Freezing phenomenon:

Browse all the conditions that are associated with Freezing phenomenon:


How the study uses the data?

The study uses data from the FDA. It is based on sodium chloride (the active ingredients of Sodium chloride) and Sodium chloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: