Soliris and Mean cell haemoglobin increased - a phase IV clinical study of FDA data

Summary:

Mean cell haemoglobin increased is reported as a side effect among people who take Soliris (eculizumab), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Vitamin B12, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Mean cell haemoglobin increased when taking Soliris. It is created by eHealthMe based on reports of 58,774 people who have side effects when taking Soliris from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Mean cell haemoglobin increased?

Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood) is found to be associated with 309 drugs and 362 conditions by eHealthMe. Check the latest studies of Mean cell haemoglobin increased.

On Jul, 19, 2026

58,774 people reported to have side effects when taking Soliris.
Among them, 86 people (0.15%) have Mean cell haemoglobin increased.

Could Soliris cause Mean cell haemoglobin increased?

Among these 86 people:

How long have people been on Soliris when they have Mean cell haemoglobin increased? *

What is the gender of people who have Mean cell haemoglobin increased when taking Soliris? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Mean cell haemoglobin increased when taking Soliris? *

What are other drugs people take besides Soliris? *

What are other side effects people have besides Mean cell haemoglobin increased? *

Mean Cell Volume Increased (more than normal average red blood cell volume): 78 people, 90.70%
Red Blood Cell Count Decreased: 76 people, 88.37%
Haemoglobin Decreased: 73 people, 84.88%
Haematocrit Decreased: 72 people, 83.72%
Red Cell Distribution Width Increased: 52 people, 60.47%
White Blood Cell Count Decreased: 43 people, 50.00%
Blood Lactate Dehydrogenase Increased: 42 people, 48.84%
Thrombocytopenia (decrease of platelets in blood): 41 people, 47.67%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 31 people, 36.05%
Blood Bilirubin Increased: 30 people, 34.88%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 70 people, 81.40%
Iron Overload: 4 people, 4.65%
Pvt: 2 people, 2.33%
Pain In Extremity: 2 people, 2.33%
Haemorrhage (bleeding): 2 people, 2.33%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 2 people, 2.33%
White Blood Cell Count Decreased: 1 person, 1.16%
Vitamin B12 Deficiency: 1 person, 1.16%
Insomnia (sleeplessness): 1 person, 1.16%
Hypercoagulation (increased tendency for clotting of the blood): 1 person, 1.16%

* Approximation only. Some reports may have incomplete information.

Do you take Soliris and have Mean cell haemoglobin increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soliris:

Soliris (58,821 reports)

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mean cell haemoglobin increased:

Mean cell haemoglobin increased (309 drugs)

Browse all the conditions that are associated with Mean cell haemoglobin increased:

Mean cell haemoglobin increased (362 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eculizumab (the active ingredients of Soliris) and Soliris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.