Solu-medrol and Atrioventricular block - a phase IV clinical study of FDA data

Summary:

Atrioventricular block is reported as a side effect among people who take Solu-medrol (methylprednisolone sodium succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Atrioventricular block when taking Solu-medrol. It is created by eHealthMe based on reports of 39,265 people who have side effects when taking Solu-medrol from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Atrioventricular block?

Atrioventricular block (heart block) is found to be associated with 740 drugs and 877 conditions by eHealthMe. Check the latest studies of Atrioventricular block.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

39,265 people reported to have side effects when taking Solu-medrol.
Among them, 23 people (0.06%) have Atrioventricular block.

Could Solu-medrol cause Atrioventricular block?

Among these 23 people:

How long have people been on Solu-medrol when they have Atrioventricular block? *

What is the gender of people who have Atrioventricular block when taking Solu-medrol? *

female: 52.17 %
male: 47.83 %

What is the age of people who have Atrioventricular block when taking Solu-medrol? *

What are other drugs people take besides Solu-medrol? *

What are other side effects people have besides Atrioventricular block? *

Hypotension (abnormally low blood pressure): 10 people, 43.48%
Fainting (loss of consciousness and postural tone): 10 people, 43.48%
Cardiac Arrest: 9 people, 39.13%
Dizziness: 8 people, 34.78%
Weakness: 6 people, 26.09%
Nausea (feeling of having an urge to vomit): 6 people, 26.09%
Fever: 6 people, 26.09%
Insomnia (sleeplessness): 6 people, 26.09%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 21.74%
Bradycardia (abnormally slow heart action): 5 people, 21.74%

What are the existing conditions these people have? *

Abnormal Behavior: 4 people, 17.39%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 17.39%
Lipidosis (disorder of lipid metabolism involving abnormal accumulation of lipids in the reticuloendothelial cells): 2 people, 8.70%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 2 people, 8.70%
Hiv Infection: 1 person, 4.35%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 1 person, 4.35%
Behcet's Syndrome (involves inflammation of the blood vessels): 1 person, 4.35%
Bleeding Disorders: 1 person, 4.35%
Blood Phosphorus Decreased: 1 person, 4.35%
Diarrhea: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and have Atrioventricular block?

- Check whether Atrioventricular block is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Solu-medrol:

Solu-medrol (39,410 reports)

Atrioventricular block treatments and more:

Atrioventricular block (9,348 reports)

How severe was Atrioventricular block and when was it recovered:

Atrioventricular block in Solu-medrol

Expand to all the drugs that have ingredients of methylprednisolone sodium succinate:

Atrioventricular block and drugs with ingredients of methylprednisolone sodium succinate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrioventricular block:

Atrioventricular block (740 drugs)

Browse all the conditions that are associated with Atrioventricular block:

Atrioventricular block (877 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Solu-medrol) and Solu-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.