Sonata and Nightmares - a phase IV clinical study of FDA data

Summary:

Nightmares is reported as a side effect among people who take Sonata (zaleplon), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Oxycontin, and have Pain.

The phase IV clinical study analyzes which people have Nightmares when taking Sonata. It is created by eHealthMe based on reports of 3,092 people who have side effects when taking Sonata from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Nightmares?

Nightmares (unpleasant dreams) is found to be associated with 1,319 drugs and 1,914 conditions by eHealthMe. Check the latest studies of Nightmares.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

3,092 people reported to have side effects when taking Sonata.
Among them, 51 people (1.65%) have Nightmares.

Among these 51 people:

How long have people been on Sonata when they have Nightmares? *

What is the gender of people who have Nightmares when taking Sonata? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Nightmares when taking Sonata? *

What are other drugs people take besides Sonata? *

What are other side effects people have besides Nightmares? *

Depression: 26 people, 50.98%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 24 people, 47.06%
Drug Dependence: 23 people, 45.10%
Stress And Anxiety: 22 people, 43.14%
Suicidal Ideation: 17 people, 33.33%
Oedema Peripheral (superficial swelling): 16 people, 31.37%
Confusional State: 15 people, 29.41%
Agitation (state of anxiety or nervous excitement): 14 people, 27.45%
Nausea (feeling of having an urge to vomit): 13 people, 25.49%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 13 people, 25.49%

What are the existing conditions these people have? *

Pain: 15 people, 29.41%
Depression: 8 people, 15.69%
Hiv Infection: 6 people, 11.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.88%
Rashes (redness): 2 people, 3.92%
Neuralgia (pain in one or more nerves): 2 people, 3.92%
Migraine (headache): 2 people, 3.92%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 3.92%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 1.96%
Osteoporosis (bones weak and more likely to break): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and have Nightmares?

- Check whether Nightmares is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sonata:

Sonata (3,330 reports)

Nightmares treatments and more:

Nightmares (42,077 reports)

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nightmares:

Nightmares (1,319 drugs)

Browse all the conditions that are associated with Nightmares:

Nightmares (1,914 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zaleplon (the active ingredients of Sonata) and Sonata (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.