Sovaldi and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Sovaldi (sofosbuvir), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Olysio, and have Hepatitis c.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Sovaldi. It is created by eHealthMe based on reports of 12,681 people who have side effects when taking Sovaldi from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,444 drugs and 2,019 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Jun, 19, 2026

12,681 people reported to have side effects when taking Sovaldi.
Among them, 52 people (0.41%) have Hepatic function abnormal.

Could Sovaldi cause Hepatic function abnormal?

Among these 52 people:

How long have people been on Sovaldi when they have Hepatic function abnormal? *

What is the gender of people who have Hepatic function abnormal when taking Sovaldi? *

female: 36.73 %
male: 63.27 %

What is the age of people who have Hepatic function abnormal when taking Sovaldi? *

What are other drugs people take besides Sovaldi? *

What are other side effects people have besides Hepatic function abnormal? *

Abdominal Pain: 8 people, 15.38%
Nausea (feeling of having an urge to vomit): 8 people, 15.38%
Hepatitis C: 8 people, 15.38%
Hepatic Failure (liver failure): 8 people, 15.38%
Acute Kidney Failure: 7 people, 13.46%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 6 people, 11.54%
Pvt: 6 people, 11.54%
Drug Ineffective: 6 people, 11.54%
Blood Test Abnormal: 5 people, 9.62%
Fever: 5 people, 9.62%

What are the existing conditions these people have? *

Hepatitis C: 25 people, 48.08%
Peritonitis Bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial): 2 people, 3.85%
Oedema (fluid collection in tissue): 2 people, 3.85%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 3.85%
Hepatic Failure (liver failure): 2 people, 3.85%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 2 people, 3.85%
Abdominal Discomfort: 2 people, 3.85%
Pain: 1 person, 1.92%
Osteoporosis (bones weak and more likely to break): 1 person, 1.92%
Insomnia (sleeplessness): 1 person, 1.92%

* Approximation only. Some reports may have incomplete information.

Do you take Sovaldi and have Hepatic function abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sovaldi:

Sovaldi (12,697 reports)

Browse all side effects of Sovaldi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic function abnormal:

Hepatic function abnormal (1,444 drugs)

Browse all the conditions that are associated with Hepatic function abnormal:

Hepatic function abnormal (2,019 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir (the active ingredients of Sovaldi) and Sovaldi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.