Spiriva and Herpes simplex - a phase IV clinical study of FDA data

Summary:

Herpes simplex is reported as a side effect among people who take Spiriva (tiotropium bromide monohydrate), especially for people who are female, 60+ old, also take Advair Diskus 100/50, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Herpes simplex when taking Spiriva. It is created by eHealthMe based on reports of 155,418 people who have side effects when taking Spiriva from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Herpes simplex?

Herpes simplex (herpes simplex is a common viral infection) is found to be associated with 713 drugs and 896 conditions by eHealthMe. Check the latest studies of Herpes simplex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

155,418 people reported to have side effects when taking Spiriva.
Among them, 31 people (0.02%) have Herpes simplex.

Among these 31 people:

What is the gender of people who have Herpes simplex when taking Spiriva? *

female: 70 %
male: 30 %

What is the age of people who have Herpes simplex when taking Spiriva? *

What are other drugs people take besides Spiriva? *

What are other side effects people have besides Herpes simplex? *

Stress And Anxiety: 13 people, 41.94%
Pain: 13 people, 41.94%
Fever: 12 people, 38.71%
Death: 12 people, 38.71%
Indigestion: 12 people, 38.71%
Constipation: 12 people, 38.71%
Emotional Distress: 11 people, 35.48%
Ascites (accumulation of fluid in the abdominal cavity): 11 people, 35.48%
Injury: 11 people, 35.48%
Leukocytosis (increased white blood cells): 11 people, 35.48%

What are the existing conditions these people have? *

Stress And Anxiety: 12 people, 38.71%
Pain: 11 people, 35.48%
Breast Cancer: 10 people, 32.26%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 10 people, 32.26%
High Blood Pressure: 3 people, 9.68%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 6.45%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.45%
Nausea (feeling of having an urge to vomit): 2 people, 6.45%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 1 person, 3.23%
Dry Eyes (lack of adequate tears): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and have Herpes simplex?

- Check whether Herpes simplex is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spiriva:

Spiriva (156,666 reports)

Herpes simplex treatments and more:

Herpes simplex (13,420 reports)

How severe was Herpes simplex and when was it recovered:

Herpes simplex in Spiriva

Expand to all the drugs that have ingredients of tiotropium bromide monohydrate:

Herpes simplex and drugs with ingredients of tiotropium bromide monohydrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herpes simplex:

Herpes simplex (713 drugs)

Browse all the conditions that are associated with Herpes simplex:

Herpes simplex (896 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide monohydrate (the active ingredients of Spiriva) and Spiriva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.