Spironolactone and Glossitis - a phase IV clinical study of FDA data

Summary:

Glossitis is reported as a side effect among people who take Spironolactone (spironolactone), especially for people who are female, 60+ old, also take Furosemide, and have Chronic myeloid leukaemia.

The phase IV clinical study analyzes which people have Glossitis when taking Spironolactone. It is created by eHealthMe based on reports of 119,147 people who have side effects when taking Spironolactone from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Glossitis?

Glossitis (infection of tongue with soreness) is found to be associated with 519 drugs and 868 conditions by eHealthMe. Check the latest studies of Glossitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

119,147 people reported to have side effects when taking Spironolactone.
Among them, 20 people (0.02%) have Glossitis.

Among these 20 people:

What is the gender of people who have Glossitis when taking Spironolactone? *

female: 75 %
male: 25 %

What is the age of people who have Glossitis when taking Spironolactone? *

What are other drugs people take besides Spironolactone? *

What are other side effects people have besides Glossitis? *

Nausea (feeling of having an urge to vomit): 7 people, 35.00%
Weakness: 6 people, 30.00%
Fatigue (feeling of tiredness): 5 people, 25.00%
Headache (pain in head): 5 people, 25.00%
Weight Decreased: 4 people, 20.00%
Diarrhea: 4 people, 20.00%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 4 people, 20.00%
Rashes (redness): 4 people, 20.00%
Ageusia (loss of taste functions of the tongue): 4 people, 20.00%
Throat Irritation: 3 people, 15.00%

What are the existing conditions these people have? *

Cardiac Failure Congestive: 3 people, 15.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 15.00%
High Blood Cholesterol: 2 people, 10.00%
Heart Rate Irregular: 2 people, 10.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.00%
Asthma: 2 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.00%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 5.00%
Constipation: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and have Glossitis?

- Check whether Glossitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spironolactone:

Spironolactone (122,947 reports)

Glossitis treatments and more:

Glossitis (5,292 reports)

Browse all side effects of Spironolactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glossitis:

Glossitis (519 drugs)

Browse all the conditions that are associated with Glossitis:

Glossitis (868 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Spironolactone) and Spironolactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.