Spironolactone and Panniculitis - a phase IV clinical study of FDA data

Summary:

Panniculitis is reported as a side effect among people who take Spironolactone (spironolactone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Furosemide, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Panniculitis when taking Spironolactone. It is created by eHealthMe based on reports of 119,147 people who have side effects when taking Spironolactone from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Panniculitis?

Panniculitis (inflammation of the subcutaneous fat) is found to be associated with 278 drugs and 404 conditions by eHealthMe. Check the latest studies of Panniculitis.



On Jul, 22, 2026

119,147 people reported to have side effects when taking Spironolactone.
Among them, 12 people (0.01%) have Panniculitis.

Could Spironolactone cause Panniculitis?

Among these 12 people:

How long have people been on Spironolactone when they have Panniculitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Panniculitis when taking Spironolactone? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Panniculitis when taking Spironolactone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 12.5 %
  • 50-59: 12.5 %
  • 60+: 62.5 %

What are other drugs people take besides Spironolactone? *

  1. Prednisolone: 5 people, 41.67%
  2. Furosemide: 5 people, 41.67%
  3. Arava: 4 people, 33.33%
  4. Hydrochlorothiazide: 3 people, 25.00%
  5. Coumadin: 3 people, 25.00%
  6. Enalapril Maleate: 3 people, 25.00%
  7. Folic Acid: 3 people, 25.00%
  8. Zofran: 3 people, 25.00%
  9. Neurontin: 3 people, 25.00%
  10. Acetaminophen: 3 people, 25.00%

What are other side effects people have besides Panniculitis? *

  1. Rashes (redness): 6 people, 50.00%
  2. Cardiac Murmur (an heart sound in valve abnormality): 5 people, 41.67%
  3. Insomnia (sleeplessness): 5 people, 41.67%
  4. Pain In Extremity: 5 people, 41.67%
  5. Pain: 5 people, 41.67%
  6. Night Sweats (sweating in night): 4 people, 33.33%
  7. Cough: 4 people, 33.33%
  8. Nausea (feeling of having an urge to vomit): 4 people, 33.33%
  9. Dysaesthesia (abnormal sensation): 3 people, 25.00%
  10. Depression: 3 people, 25.00%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 33.33%
  2. Psoriasis (immune-mediated disease that affects the skin): 2 people, 16.67%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 16.67%
  4. High Blood Cholesterol: 2 people, 16.67%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 16.67%
  6. Urinary Tract Infection: 1 person, 8.33%
  7. Nausea And Vomiting: 1 person, 8.33%
  8. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 8.33%
  9. Gastrointestinal Ulcer: 1 person, 8.33%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and have Panniculitis?

- Check whether Panniculitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spironolactone:

Panniculitis treatments and more:

How severe was Panniculitis and when was it recovered:

Expand to all the drugs that have ingredients of spironolactone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spironolactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panniculitis:

Browse all the conditions that are associated with Panniculitis:


How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Spironolactone) and Spironolactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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