Sprintec and Vaginal discharge - a phase IV clinical study of FDA data

Summary:

Vaginal discharge is reported as a side effect among people who take Sprintec (ethinyl estradiol; norgestimate), especially for people who are 20-29 old, also take Plan B One-Step, and have Ectopic acth syndrome.

The phase IV clinical study analyzes which people have Vaginal discharge when taking Sprintec. It is created by eHealthMe based on reports of 3,556 people who have side effects when taking Sprintec from the FDA, and is updated regularly.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

What is Vaginal discharge?

Vaginal discharge is found to be associated with 657 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Vaginal discharge.



On Apr, 12, 2026

3,556 people reported to have side effects when taking Sprintec.
Among them, 11 people (0.31%) have Vaginal discharge.

Could Sprintec cause Vaginal discharge?

Among these 11 people:

What is the age of people who have Vaginal discharge when taking Sprintec? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 20 %
  • 20-29: 80 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Sprintec? *

  1. Plan B One-Step: 5 people, 45.45%
  2. Zanaflex: 2 people, 18.18%
  3. Soliqua 100/33: 2 people, 18.18%
  4. Plavix: 2 people, 18.18%
  5. Penlac: 2 people, 18.18%
  6. Diflucan: 2 people, 18.18%
  7. Korlym: 2 people, 18.18%
  8. Mirapex: 2 people, 18.18%
  9. Metolazone: 1 person, 9.09%
  10. Aspirin: 1 person, 9.09%

What are other side effects people have besides Vaginal discharge? *

  1. Amenorrhea (absence of a menstrual period in a woman of reproductive age): 3 people, 27.27%
  2. Menstruation Irregular: 2 people, 18.18%
  3. Fatigue (feeling of tiredness): 2 people, 18.18%
  4. Headache (pain in head): 2 people, 18.18%
  5. Hot Flush (sudden feelings of heat): 2 people, 18.18%
  6. Itching: 2 people, 18.18%
  7. Pelvic Pain: 1 person, 9.09%
  8. Menstruation Delayed (late menstruation cycle): 1 person, 9.09%
  9. Maternal Exposure During Pregnancy (use of substance during pregnancy): 1 person, 9.09%
  10. Vulvovaginal Pruritus (vulvovaginal severe itching): 1 person, 9.09%

What are the existing conditions these people have? *

  1. Ectopic Acth Syndrome (a type of cancer-usually associated with the lung): 2 people, 18.18%
  2. Menstruation Irregular: 1 person, 9.09%
  3. Hyperchlorhydria (gastric acid levels are higher in stomach): 1 person, 9.09%
  4. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Sprintec and have Vaginal discharge?

- Check whether Vaginal discharge is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sprintec:

Vaginal discharge treatments and more:

How severe was Vaginal discharge and when was it recovered:

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sprintec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal discharge:

Browse all the conditions that are associated with Vaginal discharge:


How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Sprintec) and Sprintec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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