Stivarga and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Stivarga (regorafenib), especially for people who are 60+ old, have been taking the drug for < 1 month also take Adalat Cc, and have Colon cancer.

The phase IV clinical study analyzes which people have Hot flush when taking Stivarga. It is created by eHealthMe based on reports of 9,530 people who have side effects when taking Stivarga from the FDA, and is updated regularly.

What is Stivarga?

Stivarga has active ingredients of regorafenib. eHealthMe is studying from 9,539 Stivarga users. Check the latest studies of Stivarga.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,769 drugs and 2,346 conditions by eHealthMe. Check the latest studies of Hot flush.

On May, 12, 2026

9,530 people reported to have side effects when taking Stivarga.
Among them, 24 people (0.25%) have Hot flush.

Among these 24 people:

How long have people been on Stivarga when they have Hot flush? *

What is the age of people who have Hot flush when taking Stivarga? *

What are other drugs people take besides Stivarga? *

Vitamin D3: 2 people, 8.33%
Micardis: 2 people, 8.33%
Metoclopramide Hcl: 2 people, 8.33%
Lisinopril And Hydrochlorothiazide: 2 people, 8.33%
Adalat Cc: 2 people, 8.33%
Zarxio: 1 person, 4.17%
Tylenol: 1 person, 4.17%
Tessalon: 1 person, 4.17%
Sandostatin: 1 person, 4.17%
Ondansetron: 1 person, 4.17%

What are other side effects people have besides Hot flush? *

Fatigue (feeling of tiredness): 12 people, 50.00%
Diarrhea: 11 people, 45.83%
High Blood Pressure: 10 people, 41.67%
Nausea (feeling of having an urge to vomit): 9 people, 37.50%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 8 people, 33.33%
Pain In Extremity: 7 people, 29.17%
Neuropathy Peripheral (surface nerve damage): 7 people, 29.17%
Nausea And Vomiting: 7 people, 29.17%
Rashes (redness): 6 people, 25.00%
Pain: 6 people, 25.00%

What are the existing conditions these people have? *

Colon Cancer: 11 people, 45.83%
Rectal Cancer (cancer of rectum): 3 people, 12.50%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 3 people, 12.50%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 3 people, 12.50%
Metastases To Liver (cancer spreads to liver): 2 people, 8.33%
Colon Cancer Stage Iv: 2 people, 8.33%
Thymoma Malignant (a cancerous tumour originating from the epithelial cells of the thymus): 1 person, 4.17%
Rectosigmoid Cancer (cancer that originates in the rectum and sigmoid colon): 1 person, 4.17%
Pain: 1 person, 4.17%
Metastases To Lymph Nodes (cancer spreads to lymph node): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Stivarga and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Stivarga:

Stivarga (9,539 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Stivarga:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,769 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,346 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on regorafenib (the active ingredients of Stivarga) and Stivarga (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.