Stribild and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Stribild (cobicistat; elvitegravir; emtricitabine; tenofovir disoproxil fumarate), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Truvada, and have Depression.

The phase IV clinical study analyzes which people have Malaise when taking Stribild. It is created by eHealthMe based on reports of 16,366 people who have side effects when taking Stribild from the FDA, and is updated regularly.

What is Stribild?

Stribild has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 16,425 Stribild users. Check the latest studies of Stribild.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,488 drugs and 5,129 conditions by eHealthMe. Check the latest studies of Malaise.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

16,366 people reported to have side effects when taking Stribild.
Among them, 40 people (0.24%) have Malaise.

Among these 40 people:

How long have people been on Stribild when they have Malaise? *

What is the gender of people who have Malaise when taking Stribild? *

female: 2.7 %
male: 97.3 %

What is the age of people who have Malaise when taking Stribild? *

What are other drugs people take besides Stribild? *

What are other side effects people have besides Malaise? *

Weakness: 9 people, 22.50%
Emotional Distress: 8 people, 20.00%
Stress And Anxiety: 8 people, 20.00%
Pain: 8 people, 20.00%
Diarrhea: 7 people, 17.50%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 7 people, 17.50%
Fatigue (feeling of tiredness): 6 people, 15.00%
Abdominal Pain: 4 people, 10.00%
Anaemia (lack of blood): 4 people, 10.00%
Chronic Kidney Disease: 4 people, 10.00%

What are the existing conditions these people have? *

Depression: 4 people, 10.00%
Hepatitis C: 3 people, 7.50%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 5.00%
High Blood Cholesterol: 2 people, 5.00%
Gastric Disorder (disease of stomach): 2 people, 5.00%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 5.00%
Diabetes: 2 people, 5.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 2.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 2.50%
Hiv Test Positive: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Stribild and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Stribild:

Stribild (16,425 reports)

Malaise treatments and more:

Malaise (529,933 reports)

How severe was Malaise and when was it recovered:

Malaise in Stribild

Expand to all the drugs that have ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir disoproxil fumarate:

Malaise and drugs with ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir disoproxil fumarate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Stribild:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Malaise (3,488 drugs)

Browse all the conditions that are associated with Malaise:

Malaise (5,129 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cobicistat; elvitegravir; emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Stribild) and Stribild (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.