Sulfamethoxazole and Bladder transitional cell carcinoma - a phase IV clinical study of FDA data

Summary:

Bladder transitional cell carcinoma is reported as a side effect among people who take Sulfamethoxazole (sulfamethoxazole), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Doxycycline, and have Cardiac failure.

The phase IV clinical study analyzes which people have Bladder transitional cell carcinoma when taking Sulfamethoxazole. It is created by eHealthMe based on reports of 13,142 people who have side effects when taking Sulfamethoxazole from the FDA, and is updated regularly.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

What is Bladder transitional cell carcinoma?

Bladder transitional cell carcinoma (types of bladder cancer) is found to be associated with 203 drugs and 229 conditions by eHealthMe. Check the latest studies of Bladder transitional cell carcinoma.

On Jul, 03, 2026

13,142 people reported to have side effects when taking Sulfamethoxazole.
Among them, 15 people (0.11%) have Bladder transitional cell carcinoma.

Could Sulfamethoxazole cause Bladder transitional cell carcinoma?

Among these 15 people:

How long have people been on Sulfamethoxazole when they have Bladder transitional cell carcinoma? *

What is the gender of people who have Bladder transitional cell carcinoma when taking Sulfamethoxazole? *

female: 93.33 %
male: 6.67 %

What is the age of people who have Bladder transitional cell carcinoma when taking Sulfamethoxazole? *

What are other drugs people take besides Sulfamethoxazole? *

Hydrocortisone Butyrate: 14 people, 93.33%
Levothyroxine Sodium: 14 people, 93.33%
Azithromycin: 14 people, 93.33%
Cefpodoxime Proxetil: 14 people, 93.33%
Chlorthalidone: 14 people, 93.33%
Ciprofloxacin Hydrochloride: 14 people, 93.33%
Clindagel: 14 people, 93.33%
Clindamycin Hydrochloride: 14 people, 93.33%
Doxazosin Mesylate: 14 people, 93.33%
Doxycycline: 14 people, 93.33%

What are other side effects people have besides Bladder transitional cell carcinoma? *

Second Primary Malignancy (after getting cure a cancer, a new cancer development): 4 people, 26.67%

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 93.33%
Cardiac Failure: 14 people, 93.33%
Pain: 1 person, 6.67%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
Immunodeficiency: 1 person, 6.67%
Constipation: 1 person, 6.67%
Bone Disorder: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfamethoxazole and have Bladder transitional cell carcinoma?

- Check whether Bladder transitional cell carcinoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sulfamethoxazole:

Sulfamethoxazole (13,360 reports)

Browse all side effects of Sulfamethoxazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder transitional cell carcinoma:

Bladder transitional cell carcinoma (203 drugs)

Browse all the conditions that are associated with Bladder transitional cell carcinoma:

Bladder transitional cell carcinoma (229 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole (the active ingredients of Sulfamethoxazole) and Sulfamethoxazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.