Symbyax and Pancreatitis - a phase IV clinical study of FDA data

Summary:

Pancreatitis is reported as a side effect among people who take Symbyax (fluoxetine hydrochloride; olanzapine), especially for people who are male, 40-49 old, have been taking the drug for 1 - 2 years also take Zyprexa, and have Psychotic disorder.

The phase IV clinical study analyzes which people have Pancreatitis when taking Symbyax. It is created by eHealthMe based on reports of 1,347 people who have side effects when taking Symbyax from the FDA, and is updated regularly.

What is Symbyax?

Symbyax has active ingredients of fluoxetine hydrochloride; olanzapine. It is often used in depression. eHealthMe is studying from 1,449 Symbyax users. Check the latest studies of Symbyax.

What is Pancreatitis?

Pancreatitis (inflammation of pancreas) is found to be associated with 1,765 drugs and 2,025 conditions by eHealthMe. Check the latest studies of Pancreatitis.



On Jul, 20, 2026

1,347 people reported to have side effects when taking Symbyax.
Among them, 65 people (4.83%) have Pancreatitis.

Could Symbyax cause Pancreatitis?

Among these 65 people:

How long have people been on Symbyax when they have Pancreatitis? *

  • < 1 month: 3.85 %
  • 1 - 6 months: 23.08 %
  • 6 - 12 months: 11.54 %
  • 1 - 2 years: 30.77 %
  • 2 - 5 years: 23.08 %
  • 5 - 10 years: 7.69 %
  • 10+ years: 0.0 %

What is the gender of people who have Pancreatitis when taking Symbyax? *

  • female: 46.15 %
  • male: 53.85 %

What is the age of people who have Pancreatitis when taking Symbyax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.81 %
  • 20-29: 4.69 %
  • 30-39: 25.0 %
  • 40-49: 43.75 %
  • 50-59: 12.5 %
  • 60+: 6.25 %

What are other drugs people take besides Symbyax? *

  1. Zyprexa: 44 people, 67.69%
  2. Seroquel: 37 people, 56.92%
  3. Depakote: 24 people, 36.92%
  4. Geodon: 22 people, 33.85%
  5. Paxil: 18 people, 27.69%
  6. Risperdal: 18 people, 27.69%
  7. Abilify: 12 people, 18.46%
  8. Celexa: 12 people, 18.46%
  9. Navane: 11 people, 16.92%
  10. Risperidone: 10 people, 15.38%

What are other side effects people have besides Pancreatitis? *

  1. Diabetes: 24 people, 36.92%
  2. High Blood Cholesterol: 23 people, 35.38%
  3. Type 2 Diabetes: 23 people, 35.38%
  4. High Blood Pressure: 17 people, 26.15%
  5. Weight Increased: 15 people, 23.08%
  6. Drowsiness: 12 people, 18.46%
  7. Hypoglycemia (low blood sugar): 10 people, 15.38%
  8. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 10 people, 15.38%
  9. Neuropathy Peripheral (surface nerve damage): 10 people, 15.38%
  10. Diarrhea: 10 people, 15.38%

What are the existing conditions these people have? *

  1. Psychotic Disorder: 5 people, 7.69%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 6.15%
  3. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 6.15%
  4. Stress And Anxiety: 3 people, 4.62%
  5. Sleep Disorder: 3 people, 4.62%
  6. Post-Traumatic Stress Disorder: 3 people, 4.62%
  7. Insomnia (sleeplessness): 3 people, 4.62%
  8. Thinking Abnormal: 1 person, 1.54%
  9. Personality Disorder: 1 person, 1.54%
  10. Mania (a state of abnormally elevated or irritable mood): 1 person, 1.54%

* Approximation only. Some reports may have incomplete information.

Do you take Symbyax and have Pancreatitis?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Symbyax:

Pancreatitis treatments and more:

How severe was Pancreatitis and when was it recovered:

Expand to all the drugs that have ingredients of fluoxetine hydrochloride; olanzapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Symbyax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pancreatitis:

Browse all the conditions that are associated with Pancreatitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride; olanzapine (the active ingredients of Symbyax) and Symbyax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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