Symlin and Chronic kidney disease - a phase IV clinical study of FDA data

Summary:

Chronic kidney disease is reported as a side effect among people who take Symlin (pramlintide acetate), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Prilosec, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Chronic kidney disease when taking Symlin. It is created by eHealthMe based on reports of 3,334 people who have side effects when taking Symlin from the FDA, and is updated regularly.

What is Symlin?

Symlin has active ingredients of pramlintide acetate. It is often used in diabetes. eHealthMe is studying from 3,359 Symlin users. Check the latest studies of Symlin.

What is Chronic kidney disease?

Chronic kidney disease is found to be associated with 1,825 drugs and 1,367 conditions by eHealthMe. Check the latest studies of Chronic kidney disease.

On Jul, 27, 2026

3,334 people reported to have side effects when taking Symlin.
Among them, 21 people (0.63%) have Chronic kidney disease.

Could Symlin cause Chronic kidney disease?

Among these 21 people:

How long have people been on Symlin when they have Chronic kidney disease? *

What is the gender of people who have Chronic kidney disease when taking Symlin? *

female: 61.11 %
male: 38.89 %

What is the age of people who have Chronic kidney disease when taking Symlin? *

What are other drugs people take besides Symlin? *

What are other side effects people have besides Chronic kidney disease? *

Acute Kidney Failure: 12 people, 57.14%
Nephrogenic Anaemia (anaemia due to kidney disease): 7 people, 33.33%
Renal Tubular Necrosis (death of kidney tubules): 5 people, 23.81%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 5 people, 23.81%
Renal Haematoma (blood collection in kidney): 4 people, 19.05%
Interstitial Nephritis (inflammation of the kidney): 4 people, 19.05%
Glomerulonephritis Chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli): 4 people, 19.05%
Renal Injury (kidney injury): 3 people, 14.29%
Nephritic Syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders): 3 people, 14.29%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 2 people, 9.52%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 76.19%
High Blood Cholesterol: 16 people, 76.19%
Blood Pressure Abnormal: 13 people, 61.90%
Pain: 13 people, 61.90%
Gout (uric acid crystals building up in the body): 11 people, 52.38%
Cardiac Disorder: 9 people, 42.86%
Sleep Disorder: 8 people, 38.10%
Depression: 5 people, 23.81%
High Blood Pressure: 4 people, 19.05%
Thyroid Diseases: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Symlin and have Chronic kidney disease?

- Check whether Chronic kidney disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Symlin:

Symlin (3,359 reports)

Browse all side effects of Symlin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic kidney disease:

Chronic kidney disease (1,825 drugs)

Browse all the conditions that are associated with Chronic kidney disease:

Chronic kidney disease (1,367 conditions)

Related publications that referenced our studies

Aalaei-Andabili, S. H., Umer, M., & Keeley, E. C., "An Adult Woman With Stage 4 Chronic Kidney Disease and a Diffuse Rash", JAMA cardiology, 2019 Jan .
Aalaei-Andabili, S. H., Umer, M., & Keeley, E. C., "An Adult Woman With Stage 4 Chronic Kidney Disease and a Diffuse Rash", JAMA cardiology, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on pramlintide acetate (the active ingredients of Symlin) and Symlin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.