Synjardy and Constipation - a phase IV clinical study of FDA data
Summary:
Constipation is reported as a side effect among people who take Synjardy (empagliflozin; metformin hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Aspirin, and have Primary amyloidosis.
The phase IV clinical study analyzes which people have Constipation when taking Synjardy. It is created by eHealthMe based on reports of 2,896 people who have side effects when taking Synjardy from the FDA, and is updated regularly.
What is Synjardy?
Synjardy has active ingredients of empagliflozin; metformin hydrochloride. eHealthMe is studying from 2,927 Synjardy users. Check the latest studies of Synjardy.
What is Constipation?
Constipation is found to be associated with 3,004 drugs and 4,579 conditions by eHealthMe. Check the latest studies of Constipation.
2,896 people reported to have side effects when taking Synjardy.
Among them, 70 people (2.42%) have Constipation.

Among these 70 people:
How long have people been on Synjardy when they have Constipation? *
What is the gender of people who have Constipation when taking Synjardy? *
What is the age of people who have Constipation when taking Synjardy? *
What are other drugs people take besides Synjardy? *
What are other side effects people have besides Constipation? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Synjardy and have Constipation?
- Check whether Constipation is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Synjardy:
- Synjardy (2,927 reports)
Constipation treatments and more:
- Constipation (337,863 reports)
How severe was Constipation and when was it recovered:
Expand to all the drugs that have ingredients of empagliflozin; metformin hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Synjardy side effects:
- Synjardy side effect: Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies) (300 reports)
- Synjardy side effect: Blood glucose increased (208 reports)
- Synjardy side effect: Nausea (feeling of having an urge to vomit) (201 reports)
- Synjardy side effect: Weight decreased (164 reports)
- Synjardy side effect: Drug ineffective (111 reports)
Browse all side effects of Synjardy:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Constipation:
- Aspirin side effect: Constipation (15,193 reports)
- Revlimid side effect: Constipation (10,593 reports)
- Prednisone side effect: Constipation (10,018 reports)
- Omeprazole side effect: Constipation (9,514 reports)
- Amlodipine side effect: Constipation (8,632 reports)
- Vitamin d side effect: Constipation (8,304 reports)
- Metformin side effect: Constipation (7,959 reports)
- Gabapentin side effect: Constipation (7,855 reports)
- Pantoprazole side effect: Constipation (7,266 reports)
- Furosemide side effect: Constipation (7,021 reports)
Browse all the drugs that are associated with Constipation:
- Constipation (3,004 drugs)
Common conditions associated with Constipation:
- Multiple myeloma: 13,777 reports
- Pain exacerbated: 12,191 reports
- Hypnosis and pain: 12,019 reports
- Hypertension: 11,619 reports
- High blood pressure: 11,579 reports
- Multiple sclerosis aggravated: 7,362 reports
- Ovarian cancer: 7,156 reports
- Cancer - ovaries: 7,146 reports
- Inflammatory bowel disease - crohn's disease: 7,083 reports
- Osteoporosis: 6,518 reports
Browse all the conditions that are associated with Constipation:
- Constipation (4,579 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on empagliflozin; metformin hydrochloride (the active ingredients of Synjardy) and Synjardy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Hawthorn vs. Accuretic, side effect and effectiveness comparison - 5 seconds ago
- Formication and drugs of ingredients of dexlansoprazole - 8 seconds ago
- Drug interactions of Amoxicillin and Miralax - 8 seconds ago
- Could Actemra cause Lung Neoplasm? - 12 seconds ago
- Could Cymbalta cause White Blood Cell Count Increased? - 21 seconds ago
- Could Baclofen cause Irritable Bowel Syndrome? - 22 seconds ago
- Potassium Chloride and Flonase drug interactions for women aged 50-59 - 28 seconds ago
- Drug interactions of Imodium and Sinemet - 28 seconds ago
- Digoxin and Bundle Branch Block Left for Men aged 50-59 - 29 seconds ago
- Ipratropium Bromide and Arrhythmias for Women aged 60+ - 31 seconds ago