Synribo and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Synribo (omacetaxine mepesuccinate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Norco, and have Chronic myeloid leukaemia.

The phase IV clinical study analyzes which people have Hypotension when taking Synribo. It is created by eHealthMe based on reports of 799 people who have side effects when taking Synribo from the FDA, and is updated regularly.

What is Synribo?

Synribo has active ingredients of omacetaxine mepesuccinate. eHealthMe is studying from 799 Synribo users. Check the latest studies of Synribo.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,364 drugs and 4,753 conditions by eHealthMe. Check the latest studies of Hypotension.



On Jul, 06, 2026

799 people reported to have side effects when taking Synribo.
Among them, 12 people (1.5%) have Hypotension.

Could Synribo cause Hypotension?

Among these 12 people:

How long have people been on Synribo when they have Hypotension? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypotension when taking Synribo? *

  • female: 41.67 %
  • male: 58.33 %

What is the age of people who have Hypotension when taking Synribo? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 11.11 %
  • 60+: 88.89 %

What are other drugs people take besides Synribo? *

  1. Norco: 3 people, 25.00%
  2. Vidaza: 2 people, 16.67%
  3. Revatio: 2 people, 16.67%
  4. Opsumit: 2 people, 16.67%
  5. Zyloprim: 1 person, 8.33%
  6. Lasix: 1 person, 8.33%
  7. Briviact: 1 person, 8.33%
  8. Cardizem: 1 person, 8.33%
  9. Coreg: 1 person, 8.33%
  10. Coumadin: 1 person, 8.33%

What are other side effects people have besides Hypotension? *

  1. Dizziness: 3 people, 25.00%
  2. Pneumonia: 3 people, 25.00%
  3. Weakness: 3 people, 25.00%
  4. Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 2 people, 16.67%
  5. Blood Count Abnormal: 2 people, 16.67%
  6. Hypervolaemia (abnormally increased volume of blood): 2 people, 16.67%
  7. Dehydration (dryness resulting from the removal of water): 2 people, 16.67%
  8. Fatigue (feeling of tiredness): 2 people, 16.67%
  9. Acute Kidney Failure: 1 person, 8.33%
  10. Back Pain: 1 person, 8.33%

What are the existing conditions these people have? *

  1. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 7 people, 58.33%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 16.67%
  3. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 16.67%
  4. High Blood Pressure: 2 people, 16.67%
  5. High Blood Cholesterol: 2 people, 16.67%
  6. Gout (uric acid crystals building up in the body): 2 people, 16.67%
  7. Prostatomegaly (enlargement of the prostate): 1 person, 8.33%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%
  9. Enlarged Prostate: 1 person, 8.33%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Synribo and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Synribo:

Hypotension treatments and more:

How severe was Hypotension and when was it recovered:

Expand to all the drugs that have ingredients of omacetaxine mepesuccinate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Synribo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Browse all the conditions that are associated with Hypotension:


How the study uses the data?

The study uses data from the FDA. It is based on omacetaxine mepesuccinate (the active ingredients of Synribo) and Synribo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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