Synthroid and Constipation - a phase IV clinical study of FDA data
Summary:
Constipation is found among people who take Synthroid, especially for people who are female, 60+ old, have been taking the drug for 10+ years.
The phase IV clinical study analyzes which people take Synthroid and have Constipation. It is created by eHealthMe based on reports of 215,853 people who have side effects when taking Synthroid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
215,853 people reported to have side effects when taking Synthroid.
Among them, 5,988 people (2.77%) have Constipation.
What is Synthroid?
Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 227,054 Synthroid users for its effectiveness, alternative drugs and more.
What is Constipation?
Constipation is found to be associated with 4,527 drugs and 4,438 conditions by eHealthMe.
Number of Synthroid and Constipation reports submitted per year:

Time on Synthroid when people have Constipation *:
Gender of people who have Constipation when taking Synthroid*:
Age of people who have Constipation when taking Synthroid *:
Common drugs people take besides Synthroid *:
Common side effects people have besides Constipation *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Synthroid and have Constipation?
Check whether Constipation is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Constipation and when was it recovered:
Expand to all the drugs that have ingredients of levothyroxine sodium:
- Constipation and drugs with ingredients of levothyroxine sodium (13,752 reports)
Alternative drugs to, pros and cons of Synthroid:
- Synthroid (227,054 reports)
Common Synthroid side effects:
- Fatigue (feeling of tiredness): 20,619 reports
- Drug ineffective: 16,072 reports
- Headache (pain in head): 14,633 reports
- Pain: 13,929 reports
- Diarrhea: 13,797 reports
- Weakness: 13,556 reports
- Breathing difficulty: 13,332 reports
Browse all side effects of Synthroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zConstipation treatments and more:
- Constipation (290,598 reports)
COVID vaccines that are related to Constipation:
- Constipation in Moderna COVID Vaccine
- Constipation in Pfizer BioNTech Covid Vaccine
- Constipation in Johnson and Johnson Covid Vaccine
Common drugs associated with Constipation:
- Aspirin: 12,725 reports
- Revlimid: 8,551 reports
- Prednisone: 7,899 reports
- Omeprazole: 7,889 reports
- Metformin: 6,511 reports
- Amlodipine: 6,487 reports
- Lisinopril: 6,160 reports
- Vitamin d: 6,151 reports
- Gabapentin: 6,092 reports
- Synthroid: 5,988 reports
All the drugs that are associated with Constipation:
- Constipation (4,527 drugs)
Common conditions associated with Constipation:
- Multiple myeloma: 11,077 reports
- Pain: 10,745 reports
- High blood pressure: 10,310 reports
- Multiple sclerosis: 6,775 reports
- Osteoporosis: 6,288 reports
- Depression: 5,357 reports
All the conditions that are associated with Constipation:
- Constipation (4,438 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Synthroid) and Synthroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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