Synthroid and Dermatitis herpetiformis - a phase IV clinical study of FDA data

Summary:

Dermatitis herpetiformis is reported as a side effect among people who take Synthroid (levothyroxine sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zocor, and have Arthritis.

The phase IV clinical study analyzes which people have Dermatitis herpetiformis when taking Synthroid. It is created by eHealthMe based on reports of 237,758 people who have side effects when taking Synthroid from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,205 Synthroid users. Check the latest studies of Synthroid.

What is Dermatitis herpetiformis?

Dermatitis herpetiformis (chronic blistering skin condition, characterized by blisters filled with a watery fluid) is found to be associated with 19 drugs and 142 conditions by eHealthMe. Check the latest studies of Dermatitis herpetiformis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

237,758 people reported to have side effects when taking Synthroid.
Among them, 15 people (0.01%) have Dermatitis herpetiformis.

Could Synthroid cause Dermatitis herpetiformis?

Among these 15 people:

How long have people been on Synthroid when they have Dermatitis herpetiformis? *

What is the gender of people who have Dermatitis herpetiformis when taking Synthroid? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Dermatitis herpetiformis when taking Synthroid? *

What are other drugs people take besides Synthroid? *

What are other side effects people have besides Dermatitis herpetiformis? *

Celiac Disease - Sprue (a disease of the small intestine): 3 people, 20.00%
Vitamin D Decreased: 1 person, 6.67%
Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 6.67%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 6.67%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 1 person, 6.67%
Clostridium Test Positive: 1 person, 6.67%
Cytomegalovirus Colitis (an inflammation of the colon from virus): 1 person, 6.67%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 6.67%
Dizziness: 1 person, 6.67%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 6.67%

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 13.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
Type 1 Diabetes: 1 person, 6.67%
Quit Smoking: 1 person, 6.67%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 6.67%
High Blood Cholesterol: 1 person, 6.67%
Dry Eyes (lack of adequate tears): 1 person, 6.67%
Diabetes: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Synthroid and have Dermatitis herpetiformis?

- Check whether Dermatitis herpetiformis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Synthroid:

Synthroid (249,205 reports)

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dermatitis herpetiformis:

Dermatitis herpetiformis (19 drugs)

Browse all the conditions that are associated with Dermatitis herpetiformis:

Dermatitis herpetiformis (142 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Synthroid) and Synthroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.