Synthroid and Diffuse vasculitis - a phase IV clinical study of FDA data


Diffuse vasculitis is found among people who take Synthroid, especially for people who are female, 40-49 old.

The phase IV clinical study analyzes which people take Synthroid and have Diffuse vasculitis. It is created by eHealthMe based on reports of 215,853 people who have side effects when taking Synthroid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 26, 2023

215,853 people reported to have side effects when taking Synthroid.
Among them, 6 people (0.0%) have Diffuse vasculitis.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 226,976 Synthroid users for its effectiveness, alternative drugs and more.

What is Diffuse vasculitis?

Diffuse vasculitis (spread of systemic illness) is found to be associated with 118 drugs and 62 conditions by eHealthMe.

Number of Synthroid and Diffuse vasculitis reports submitted per year:

Could Synthroid cause Diffuse vasculitis?

Gender of people who have Diffuse vasculitis when taking Synthroid *:

  • female: 80 %
  • male: 20 %

Age of people who have Diffuse vasculitis when taking Synthroid *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 66.67 %
  • 50-59: 33.33 %
  • 60+: 0.0 %

Common drugs people take besides Synthroid *:

  1. Valium: 3 people, 50.00%
  2. Prevacid: 3 people, 50.00%
  3. Plavix: 2 people, 33.33%
  4. Xanax: 2 people, 33.33%
  5. Tamiflu: 2 people, 33.33%
  6. Prozac: 2 people, 33.33%
  7. Calan: 2 people, 33.33%
  8. Levoxyl: 2 people, 33.33%
  9. Nuvaring: 2 people, 33.33%
  10. Lexapro: 2 people, 33.33%

Common side effects people have besides Diffuse vasculitis *:

  1. Nausea (feeling of having an urge to vomit): 5 people, 83.33%
  2. Nausea And Vomiting: 5 people, 83.33%
  3. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 5 people, 83.33%
  4. Headache (pain in head): 5 people, 83.33%
  5. Hypotension (abnormally low blood pressure): 4 people, 66.67%
  6. Overdose: 3 people, 50.00%
  7. Drug Hypersensitivity: 3 people, 50.00%
  8. Stress And Anxiety: 3 people, 50.00%
  9. Neck Pain: 3 people, 50.00%
  10. Joint Pain: 3 people, 50.00%

Common conditions people have *:

  1. Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 2 people, 33.33%
  2. Stress And Anxiety: 2 people, 33.33%
  3. Pain: 2 people, 33.33%
  4. Migraine (headache): 2 people, 33.33%
  5. Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 16.67%
  6. Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 1 person, 16.67%
  7. Muscle Aches (muscle pain): 1 person, 16.67%
  8. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Synthroid and have Diffuse vasculitis?

Check whether Diffuse vasculitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Diffuse vasculitis and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Alternative drugs to, pros and cons of Synthroid:

Common Synthroid side effects:

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Diffuse vasculitis treatments and more:

COVID vaccines that are related to Diffuse vasculitis:

All the drugs that are associated with Diffuse vasculitis:

All the conditions that are associated with Diffuse vasculitis:

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Synthroid) and Synthroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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