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Synthroid and Ejaculation failure - a phase IV clinical study of FDA data

Summary:

Ejaculation failure is reported as a side effect among people who take Synthroid (levothyroxine sodium), especially for people who are 60+ old, also take Flomax, and have Depression.

The phase IV clinical study analyzes which people have Ejaculation failure when taking Synthroid. It is created by eHealthMe based on reports of 237,758 people who have side effects when taking Synthroid from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,194 Synthroid users. Check the latest studies of Synthroid.

What is Ejaculation failure?

Ejaculation failure is found to be associated with 131 drugs and 382 conditions by eHealthMe. Check the latest studies of Ejaculation failure.

On Feb, 22, 2026

237,758 people reported to have side effects when taking Synthroid.
Among them, 13 people (0.01%) have Ejaculation failure.

Could Synthroid cause Ejaculation failure?

Among these 13 people:

What is the age of people who have Ejaculation failure when taking Synthroid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 14.29 %
  • 60+: 71.43 %

What are other drugs people take besides Synthroid? *

  1. Flomax: 4 people, 30.77%
  2. Lamictal: 3 people, 23.08%
  3. Coumadin: 2 people, 15.38%
  4. Viagra: 2 people, 15.38%
  5. Seroquel: 2 people, 15.38%
  6. Folic Acid: 2 people, 15.38%
  7. Prednisone: 2 people, 15.38%
  8. Zocor: 2 people, 15.38%
  9. Zyprexa: 1 person, 7.69%
  10. Cymbalta: 1 person, 7.69%

What are other side effects people have besides Ejaculation failure? *

  1. Fatigue (feeling of tiredness): 6 people, 46.15%
  2. Erection Problems: 6 people, 46.15%
  3. Stress And Anxiety: 3 people, 23.08%
  4. High Blood Pressure: 3 people, 23.08%
  5. Dizziness: 3 people, 23.08%
  6. Insomnia (sleeplessness): 3 people, 23.08%
  7. Malaise (a feeling of general discomfort or uneasiness): 3 people, 23.08%
  8. Nosebleed (bleeding from nose): 2 people, 15.38%
  9. Headache (pain in head): 2 people, 15.38%
  10. Drowsiness: 2 people, 15.38%

What are the existing conditions these people have? *

  1. Depression: 3 people, 23.08%
  2. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 15.38%
  3. Erection Problems: 2 people, 15.38%
  4. Enlarged Prostate: 2 people, 15.38%
  5. Bipolar Disorder (mood disorder): 2 people, 15.38%
  6. Affective Disorder (mental disorder): 2 people, 15.38%
  7. Prostatomegaly (enlargement of the prostate): 1 person, 7.69%
  8. Papillary Thyroid Cancer: 1 person, 7.69%
  9. Neuropathy Peripheral (surface nerve damage): 1 person, 7.69%
  10. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Synthroid and have Ejaculation failure?

- Check whether Ejaculation failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Synthroid:

Ejaculation failure treatments and more:

How severe was Ejaculation failure and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ejaculation failure:

Browse all the conditions that are associated with Ejaculation failure:

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Synthroid) and Synthroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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