Synthroid and Gallbladder attack - a phase IV clinical study of FDA data

Summary:

Gallbladder attack is reported as a side effect among people who take Synthroid (levothyroxine sodium), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Yasmin, and have High blood pressure.

The phase IV clinical study analyzes which people have Gallbladder attack when taking Synthroid. It is created by eHealthMe based on reports of 237,758 people who have side effects when taking Synthroid from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,182 Synthroid users. Check the latest studies of Synthroid.

What is Gallbladder attack?

Gallbladder attack (gallstones, gallbladder disease and gallbladder pain) is found to be associated with 671 drugs and 972 conditions by eHealthMe. Check the latest studies of Gallbladder attack.

On Oct, 06, 2025

237,758 people reported to have side effects when taking Synthroid.
Among them, 126 people (0.05%) have Gallbladder attack.

Could Synthroid cause Gallbladder attack?

Among these 126 people:

How long have people been on Synthroid when they have Gallbladder attack? *

What is the gender of people who have Gallbladder attack when taking Synthroid? *

female: 85.48 %
male: 14.52 %

What is the age of people who have Gallbladder attack when taking Synthroid? *

What are other drugs people take besides Synthroid? *

What are other side effects people have besides Gallbladder attack? *

Pain: 55 people, 43.65%
Abdominal Pain Upper: 44 people, 34.92%
Gallstones (stone formation by bile component): 41 people, 32.54%
Nausea (feeling of having an urge to vomit): 36 people, 28.57%
High Blood Pressure: 32 people, 25.40%
Stress And Anxiety: 32 people, 25.40%
Malaise (a feeling of general discomfort or uneasiness): 31 people, 24.60%
Muscle Spasms (muscle contraction): 31 people, 24.60%
Nausea And Vomiting: 31 people, 24.60%
Chest Pain: 28 people, 22.22%

What are the existing conditions these people have? *

High Blood Pressure: 23 people, 18.25%
Birth Control: 19 people, 15.08%
Pancreatitis Chronic (chronic inflammation of pancreas): 19 people, 15.08%
Pain: 15 people, 11.90%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 13 people, 10.32%
High Blood Cholesterol: 13 people, 10.32%
Depression: 12 people, 9.52%
Joint Pain: 10 people, 7.94%
Carcinoid Tumor: 9 people, 7.14%
Breast Cancer Metastatic: 8 people, 6.35%

* Approximation only. Some reports may have incomplete information.

Do you take Synthroid and have Gallbladder attack?

- Check whether Gallbladder attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Synthroid:

Synthroid (249,182 reports)

Common Synthroid side effects:

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Gallbladder attack:

Browse all the drugs that are associated with Gallbladder attack:

Gallbladder attack (671 drugs)

Common conditions associated with Gallbladder attack:

Browse all the conditions that are associated with Gallbladder attack:

Gallbladder attack (972 conditions)

Drugs similar to Synthroid and Gallbladder attack :

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Synthroid) and Synthroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.