Synthroid and Multiple drug overdose - a phase IV clinical study of FDA data

Summary:

Multiple drug overdose is reported as a side effect among people who take Synthroid (levothyroxine sodium), especially for people who are female, 50-59 old, also take Lexapro, and have Depression.

The phase IV clinical study analyzes which people have Multiple drug overdose when taking Synthroid. It is created by eHealthMe based on reports of 237,758 people who have side effects when taking Synthroid from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,205 Synthroid users. Check the latest studies of Synthroid.

What is Multiple drug overdose?

Multiple drug overdose is found to be associated with 311 drugs and 393 conditions by eHealthMe. Check the latest studies of Multiple drug overdose.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

237,758 people reported to have side effects when taking Synthroid.
Among them, 38 people (0.02%) have Multiple drug overdose.

Could Synthroid cause Multiple drug overdose?

Among these 38 people:

What is the gender of people who have Multiple drug overdose when taking Synthroid? *

female: 78.95 %
male: 21.05 %

What is the age of people who have Multiple drug overdose when taking Synthroid? *

What are other drugs people take besides Synthroid? *

What are other side effects people have besides Multiple drug overdose? *

Fatigue (feeling of tiredness): 12 people, 31.58%
Hallucinations (sensations that appear real but are created by your mind): 11 people, 28.95%
Pleural Effusion (water on the lungs): 10 people, 26.32%
Delusion (a false belief or opinion): 10 people, 26.32%
Pericardial Effusion (fluid around the heart): 9 people, 23.68%
Delirium (wild excitement): 9 people, 23.68%
Drug Ineffective: 8 people, 21.05%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 8 people, 21.05%
Arrhythmias (irregular heartbeat): 7 people, 18.42%
Depression: 7 people, 18.42%

What are the existing conditions these people have? *

Depression: 17 people, 44.74%
Pain: 7 people, 18.42%
Breakthrough Pain: 5 people, 13.16%
Insomnia (sleeplessness): 5 people, 13.16%
Stress And Anxiety: 4 people, 10.53%
Nausea (feeling of having an urge to vomit): 3 people, 7.89%
Pneumonia: 2 people, 5.26%
Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 2 people, 5.26%
Ill-Defined Disorder: 1 person, 2.63%
Bipolar Disorder (mood disorder): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Synthroid and have Multiple drug overdose?

- Check whether Multiple drug overdose is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Synthroid:

Synthroid (249,205 reports)

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple drug overdose:

Multiple drug overdose (311 drugs)

Browse all the conditions that are associated with Multiple drug overdose:

Multiple drug overdose (393 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Synthroid) and Synthroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.