Tacrolimus and Bone loss - a phase IV clinical study of FDA data

Summary:

Bone loss is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are male, 50-59 old, also take Bactrim, and have Hiv infection.

The phase IV clinical study analyzes which people have Bone loss when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Bone loss?

Bone loss is found to be associated with 697 drugs and 557 conditions by eHealthMe. Check the latest studies of Bone loss.

On Jul, 12, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 22 people (0.02%) have Bone loss.

Among these 22 people:

What is the gender of people who have Bone loss when taking Tacrolimus? *

female: 38.1 %
male: 61.9 %

What is the age of people who have Bone loss when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

What are other side effects people have besides Bone loss? *

Bone Density Decreased: 15 people, 68.18%
Chronic Kidney Disease: 13 people, 59.09%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 11 people, 50.00%
Acute Kidney Failure: 10 people, 45.45%
Emotional Distress: 9 people, 40.91%
Pain: 9 people, 40.91%
Osteoporosis (bones weak and more likely to break): 8 people, 36.36%
Stress And Anxiety: 7 people, 31.82%
Multiple Fractures: 6 people, 27.27%
Tooth Loss: 6 people, 27.27%

What are the existing conditions these people have? *

Hiv Infection: 13 people, 59.09%
Vein Disorder: 1 person, 4.55%
Stress And Anxiety: 1 person, 4.55%
Pain: 1 person, 4.55%
Lung Transplant Rejection (failure of lung transplant): 1 person, 4.55%
Lung Infection: 1 person, 4.55%
Immunodeficiency Disorders: 1 person, 4.55%
High Blood Pressure: 1 person, 4.55%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 4.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Bone loss?

- Check whether Bone loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,160 reports)

Bone loss treatments and more:

Bone loss (27,142 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone loss:

Bone loss (697 drugs)

Browse all the conditions that are associated with Bone loss:

Bone loss (557 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.