Deferiprone and Deferasirox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Deferiprone (deferiprone) and Deferasirox (deferasirox). Common drug interactions include drug ineffective among females and nephrolithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Deferiprone and Deferasirox. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Deferiprone?

Deferiprone has active ingredients of deferiprone. eHealthMe is studying from 470 Deferiprone users. Check the latest studies of Deferiprone.

What is Deferasirox?

Deferasirox has active ingredients of deferasirox. eHealthMe is studying from 2,641 Deferasirox users. Check the latest studies of Deferasirox.

On Jul, 12, 2026

49 people who take Deferiprone and Deferasirox together, and have interactions are studied.

Deferiprone and Deferasirox drug interactions.

What are the common drug interactions of Deferiprone and Deferasirox, by gender? *:

female:

Drug ineffective
Nephropathy (damage to or disease of a kidney)
Drug hypersensitivity
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Neutropenia (an abnormally low number of neutrophils)
Serum ferritin increased
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Drug intolerance (drug sensitivity)
Gastroenteritis (inflammation of stomach and intestine)

male:

Nephrolithiasis (calculi in the kidneys)
Drug ineffective
Retinal dystrophy (progressive weakness and wasting of the retina)
Anaemia (lack of blood)
Bacteraemia (presence of bacteria in the blood)
Bacterial infection
Candida sepsis (candida in blood stream)
Cardiac arrest
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Extramedullary haemopoiesis (hematopoiesis occurring outside of the medulla of the bone)

What are the common drug interactions of Deferiprone and Deferasirox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Nephrolithiasis (calculi in the kidneys)
Drug ineffective
Haematuria (presence of blood in urine)
Alanine aminotransferase increased
Bacteraemia (presence of bacteria in the blood)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Glomerulonephritis membranous (nephritis with inflammation of the capillary loops in the renal glomeruli)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Joint swelling

10-19:

Bacterial infection
Candida sepsis (candida in blood stream)
Cardiac arrest
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Dyspnoea (difficult or laboured respiration)
Klebsiella infection

20-29:

Drug ineffective
Drug intolerance (drug sensitivity)
Extramedullary haemopoiesis (hematopoiesis occurring outside of the medulla of the bone)
Hypercalciuria (elevated calcium (ca+) level in the urine)
Nephrolithiasis (calculi in the kidneys)
Paralysis
Spinal cord compression
Vertebral column mass (spinal tumour)

30-39:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac siderosis (excess collection of iron in heart)
Hepatic siderosis (deposit of an abnormal quantity of iron in the liver)
Drug ineffective

40-49:

Hepatosplenomegaly (enlargement of both the liver and the spleen)
Neutropenia (an abnormally low number of neutrophils)
Serum ferritin increased

50-59:

Hepatic neoplasm malignant (liver cancer)
Hepatitis acute

60+:

Arthralgia (joint pain)
Blood creatinine increased
Cardiac failure congestive
Costovertebral angle tenderness
Deafness neurosensory
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Nephrolithiasis (calculi in the kidneys)
Sepsis (a severe blood infection that can lead to organ failure and death)
Anaemia (lack of blood)
Refractory anaemia with ringed sideroblasts (this type involves a low number of red blood cells. the existing red blood cells contain excess amounts of iron)

What are the existing conditions these people have? *

Iron Overload: 21 people, 42.86%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 10.20%

* Approximation only. Some reports may have incomplete information.

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