Tadalafil and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Tadalafil (tadalafil), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Ambrisentan, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Glaucoma when taking Tadalafil. It is created by eHealthMe based on reports of 25,126 people who have side effects when taking Tadalafil from the FDA, and is updated regularly.

What is Tadalafil?

Tadalafil has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 25,550 Tadalafil users. Check the latest studies of Tadalafil.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,233 drugs and 1,657 conditions by eHealthMe. Check the latest studies of Glaucoma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

25,126 people reported to have side effects when taking Tadalafil.
Among them, 28 people (0.11%) have Glaucoma.

Among these 28 people:

How long have people been on Tadalafil when they have Glaucoma? *

What is the gender of people who have Glaucoma when taking Tadalafil? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Glaucoma when taking Tadalafil? *

What are other drugs people take besides Tadalafil? *

Ambrisentan: 7 people, 25.00%
Nexium: 5 people, 17.86%
Losartan Potassium: 3 people, 10.71%
Allopurinol: 3 people, 10.71%
Amlodipine Besylate: 3 people, 10.71%
Metoprolol Succinate: 3 people, 10.71%
Aspirin: 3 people, 10.71%
Hydrochlorothiazide: 3 people, 10.71%
Remodulin: 3 people, 10.71%
Clonidine Hydrochloride: 3 people, 10.71%

What are other side effects people have besides Glaucoma? *

Dyspnea (difficult or laboured breathing): 8 people, 28.57%
Cataract (clouding of the lens inside the eye): 8 people, 28.57%
Joint Pain: 7 people, 25.00%
Neuropathy Peripheral (surface nerve damage): 6 people, 21.43%
Cough: 5 people, 17.86%
Optic Nerve Injury: 4 people, 14.29%
Red Cell Distribution Width Increased: 4 people, 14.29%
Pancreatitis (inflammation of pancreas): 4 people, 14.29%
Eosinophil Count Increased: 4 people, 14.29%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 14.29%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 25.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 14.29%
Penis Disorder: 2 people, 7.14%
Thyroid Diseases: 1 person, 3.57%
Indigestion: 1 person, 3.57%
Hiv Infection: 1 person, 3.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.57%
Breast Cancer Stage Ii: 1 person, 3.57%
Bipolar Disorder (mood disorder): 1 person, 3.57%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Tadalafil and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tadalafil:

Tadalafil (25,550 reports)

Glaucoma treatments and more:

Glaucoma (61,928 reports)

Browse all side effects of Tadalafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Glaucoma (1,233 drugs)

Browse all the conditions that are associated with Glaucoma:

Glaucoma (1,657 conditions)

Related publications that referenced our studies

Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on tadalafil (the active ingredients of Tadalafil) and Tadalafil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.