Tagrisso and Purpura - a phase IV clinical study of FDA data
Summary:
Purpura is reported as a side effect among people who take Tagrisso (osimertinib mesylate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Iressa, and have Lung cancer - non-small cell.
The phase IV clinical study analyzes which people have Purpura when taking Tagrisso. It is created by eHealthMe based on reports of 19,861 people who have side effects when taking Tagrisso from the FDA, and is updated regularly.
What is Tagrisso?
Tagrisso has active ingredients of osimertinib mesylate. eHealthMe is studying from 19,891 Tagrisso users. Check the latest studies of Tagrisso.
What is Purpura?
Purpura (purplish discoloration of the skin) is found to be associated with 935 drugs and 1,517 conditions by eHealthMe. Check the latest studies of Purpura.
19,861 people reported to have side effects when taking Tagrisso.
Among them, 21 people (0.11%) have Purpura.

Among these 21 people:
How long have people been on Tagrisso when they have Purpura? *
- < 1 month: 75.0 %
- 1 - 6 months: 16.67 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 8.33 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Purpura when taking Tagrisso? *
- female: 85 %
- male: 15 %
What is the age of people who have Purpura when taking Tagrisso? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 15.79 %
- 60+: 84.21 %
What are other drugs people take besides Tagrisso? *
- Iressa: 4 people, 19.05%
- Tarceva: 2 people, 9.52%
- Gilotrif: 2 people, 9.52%
- Decadron: 2 people, 9.52%
- Nexium: 1 person, 4.76%
- Edoxaban: 1 person, 4.76%
- Clexane: 1 person, 4.76%
- Amlodipine: 1 person, 4.76%
What are other side effects people have besides Purpura? *
- Rashes (redness): 6 people, 28.57%
- Vasculitis (inflammation of a blood vessel or blood vessels): 5 people, 23.81%
- Headache (pain in head): 3 people, 14.29%
- Nausea (feeling of having an urge to vomit): 3 people, 14.29%
- Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 3 people, 14.29%
- Malignant Neoplasm Progression (cancer tumour came back): 3 people, 14.29%
- Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 14.29%
- Thrombocytopenia (decrease of platelets in blood): 2 people, 9.52%
- Interstitial Lung Disease: 2 people, 9.52%
- Conjunctival Haemorrhage (bleeding underneath the conjunctiva): 2 people, 9.52%
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 16 people, 76.19%
- Gastric Ulcer (stomach ulcer): 3 people, 14.29%
- Diarrhea: 3 people, 14.29%
- Metastases To Central Nervous System (cancer spreads to central nervous system): 2 people, 9.52%
- Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 9.52%
- Insomnia (sleeplessness): 2 people, 9.52%
- High Blood Cholesterol: 2 people, 9.52%
- Chest Pain: 2 people, 9.52%
- Abdominal Discomfort: 2 people, 9.52%
- Osteoporosis (bones weak and more likely to break): 1 person, 4.76%
* Approximation only. Some reports may have incomplete information.
Do you take Tagrisso and have Purpura?
- Check whether Purpura is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tagrisso:
- Tagrisso (19,891 reports)
Purpura treatments and more:
- Purpura (10,762 reports)
How severe was Purpura and when was it recovered:
Expand to all the drugs that have ingredients of osimertinib mesylate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tagrisso:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Purpura:
- Purpura (935 drugs)
Browse all the conditions that are associated with Purpura:
- Purpura (1,517 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on osimertinib mesylate (the active ingredients of Tagrisso) and Tagrisso (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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