Targretin and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Targretin (bexarotene), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Locoid, and have Mycosis fungoides.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Targretin. It is created by eHealthMe based on reports of 1,056 people who have side effects when taking Targretin from the FDA, and is updated regularly.

What is Targretin?

Targretin has active ingredients of bexarotene. eHealthMe is studying from 1,064 Targretin users. Check the latest studies of Targretin.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,615 drugs and 2,599 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

On Jul, 18, 2026

1,056 people reported to have side effects when taking Targretin.
Among them, 98 people (9.28%) have Hypothyroidism.

Among these 98 people:

How long have people been on Targretin when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Targretin? *

female: 31.63 %
male: 68.37 %

What is the age of people who have Hypothyroidism when taking Targretin? *

What are other drugs people take besides Targretin? *

What are other side effects people have besides Hypothyroidism? *

Hypertriglyceridaemia (excess of triglycerides in the blood): 35 people, 35.71%
Dyslipidaemia (abnormal amount of lipids): 21 people, 21.43%
High Blood Cholesterol: 13 people, 13.27%
Malignant Neoplasm Progression (cancer tumour came back): 10 people, 10.20%
Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 10.20%
Hepatic Function Abnormal: 7 people, 7.14%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 7 people, 7.14%
Muscle Spasms (muscle contraction): 6 people, 6.12%
Blood Creatine Phosphokinase Increased: 6 people, 6.12%
Fever: 5 people, 5.10%

What are the existing conditions these people have? *

Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 54 people, 55.10%
Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 2.04%
Anaplastic Large Cell Lymphoma T- And Null-Cell Types (t-cell or null-cell cancer, a type of blood cancer): 2 people, 2.04%
Dyslipidaemia (abnormal amount of lipids): 2 people, 2.04%
Itching: 2 people, 2.04%
High Blood Cholesterol: 2 people, 2.04%
High Blood Pressure: 1 person, 1.02%
Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 1 person, 1.02%
Asthma: 1 person, 1.02%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 1.02%

* Approximation only. Some reports may have incomplete information.

Do you take Targretin and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Targretin:

Targretin (1,064 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,065 reports)

Browse all side effects of Targretin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,615 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,599 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on bexarotene (the active ingredients of Targretin) and Targretin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.