Tecfidera and Vaginal bleeding between periods - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding between periods is reported as a side effect among people who take Tecfidera (dimethyl fumarate), especially for people who are 40-49 old, have been taking the drug for < 1 month also take Synthroid, and have Gait disturbance.

The phase IV clinical study analyzes which people have Vaginal bleeding between periods when taking Tecfidera. It is created by eHealthMe based on reports of 129,391 people who have side effects when taking Tecfidera from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Vaginal bleeding between periods?

Vaginal bleeding between periods is found to be associated with 574 drugs and 1,468 conditions by eHealthMe. Check the latest studies of Vaginal bleeding between periods.

On Aug, 04, 2026

129,391 people reported to have side effects when taking Tecfidera.
Among them, 42 people (0.03%) have Vaginal bleeding between periods.

Could Tecfidera cause Vaginal bleeding between periods?

Among these 42 people:

How long have people been on Tecfidera when they have Vaginal bleeding between periods? *

What is the age of people who have Vaginal bleeding between periods when taking Tecfidera? *

What are other drugs people take besides Tecfidera? *

What are other side effects people have besides Vaginal bleeding between periods? *

Skin Blushing/flushing (a sudden reddening of the face, neck): 15 people, 35.71%
Heavy Or Prolong Menstrual Bleeding: 5 people, 11.90%
Abdominal Discomfort: 4 people, 9.52%
Dizziness: 4 people, 9.52%
Hot Flush (sudden feelings of heat): 4 people, 9.52%
Nausea (feeling of having an urge to vomit): 4 people, 9.52%
Menstruation Irregular: 4 people, 9.52%
Memory Loss: 3 people, 7.14%
Amenorrhea (absence of a menstrual period in a woman of reproductive age): 3 people, 7.14%
Abdominal Distension: 3 people, 7.14%

What are the existing conditions these people have? *

Gait Disturbance: 6 people, 14.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.14%
Stress And Anxiety: 2 people, 4.76%
Rickets (softening of bones): 2 people, 4.76%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 4.76%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 4.76%
Migraine (headache): 2 people, 4.76%
Tooth Disorder (tooth disease): 1 person, 2.38%
Fatigue (feeling of tiredness): 1 person, 2.38%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 2.38%

* Approximation only. Some reports may have incomplete information.

Do you take Tecfidera and have Vaginal bleeding between periods?

- Check whether Vaginal bleeding between periods is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tecfidera:

Tecfidera (129,627 reports)

Browse all side effects of Tecfidera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding between periods:

Vaginal bleeding between periods (574 drugs)

Browse all the conditions that are associated with Vaginal bleeding between periods:

Vaginal bleeding between periods (1,468 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dimethyl fumarate (the active ingredients of Tecfidera) and Tecfidera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.